{"id":"W4409087203","doi":"10.1007/s11033-025-10430-5","title":"miR-526b enhances glucose metabolism in breast cancer cells, an effect reversed by targeting the COX-2/EP4 pathway","year":2025,"lang":"en","type":"article","venue":"Molecular Biology Reports","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brandon University","funders":"Coral Reef Conservation Program; Canadian Institutes of Health Research; Canada Research Chairs; Research Manitoba; Canada Foundation for Innovation; Lotte and John Hecht Memorial Foundation","keywords":"SKBR3; Glycolysis; Cancer research; Cancer cell; Cell culture; Biology; Transfection; Oxidative phosphorylation; Biochemistry; Chemistry; Cell biology; Cancer; Metabolism","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009348046,0.0004074993,0.0005259053,0.000124027,0.0001765519,0.00003929743,0.0003465769,0.0004359565,0.00003910459],"category_scores_gemma":[0.0001093475,0.000309888,0.0002297503,0.0003850358,0.0002624537,0.00001012233,0.0001992007,0.0002936046,0.000002710904],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000321174,"about_ca_system_score_gemma":0.0002898805,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006784875,"about_ca_topic_score_gemma":0.0001840089,"domain_scores_codex":[0.9970716,0.0005756418,0.0005918843,0.001002485,0.0001452597,0.0006131685],"domain_scores_gemma":[0.9985895,0.00002653505,0.0003017934,0.000845739,0.0001197593,0.0001166994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001307993,0.0000834111,0.00164203,0.0000248697,0.0001320201,0.00003669997,0.00003777782,0.00003235941,0.983501,0.00005628078,0.009424559,0.004898232],"study_design_scores_gemma":[0.0004920016,0.00005480072,0.000883645,0.00002146921,0.00005879177,0.00005479991,0.00002874012,0.000008811795,0.6962415,0.0001018967,0.3017968,0.0002567527],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9423457,0.05094267,0.0007790219,0.0006564505,0.003966385,0.0006369282,0.0001246525,0.00003437784,0.000513769],"genre_scores_gemma":[0.9929885,0.002683474,0.0001962807,0.001908626,0.0005574053,0.0003015954,0.0005144422,0.00004486827,0.0008048035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2923722,"threshold_uncertainty_score":0.9999353,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002686553295188748,"score_gpt":0.2461118673394588,"score_spread":0.24342531404427,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}