{"id":"W4409148256","doi":"10.1111/hae.70039","title":"Trends in Treatment of Severe Haemophilia and Impact on Inhibitor Assessment by the EUHASS Registry","year":2025,"lang":"en","type":"article","venue":"Haemophilia","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Hemophilia Society","funders":"Biotest; Executive Agency for Health and Consumers; Britannia Pharmaceuticals; Grifols; Baxalta; Octapharma; Swedish Orphan Biovitrum; CSL Behring; European Association for Haemophilia and Allied Disorders; Bayer; Biogen; European Commission; Sanofi; Roche; Pfizer","keywords":"Medicine; Haemophilia A; Haemophilia; Incidence (geometry); Concomitant; Internal medicine; Haemophilia B; Cumulative incidence; Pediatrics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004295375,0.0001660442,0.0004054862,0.002159683,0.0001341867,0.000978056,0.0006381086,0.0003463309,0.001875245],"category_scores_gemma":[0.009972431,0.0001698321,0.0004913365,0.004428054,0.0002325511,0.000850753,0.0006448308,0.0004757432,0.000400287],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008408902,"about_ca_system_score_gemma":0.0009901767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01005843,"about_ca_topic_score_gemma":0.006642097,"domain_scores_codex":[0.9955297,0.00143792,0.001002854,0.0007063588,0.0009857913,0.0003373513],"domain_scores_gemma":[0.9811013,0.003632367,0.01115536,0.0008367377,0.002375053,0.0008991914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002094918,0.00002333525,0.983622,0.00009035298,0.00008899343,0.00005067261,0.00007531627,0.0004323695,0.00011521,0.0002183557,0.003481289,0.01159273],"study_design_scores_gemma":[0.00002034831,0.00009914434,0.9943562,0.00007707507,0.00003618498,0.0003490313,0.000126923,0.0007057828,0.0002367647,0.00004500357,0.00393789,0.000009576842],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9625378,0.004183753,0.0006857975,0.001073378,0.00004159515,0.00004602222,0.02578142,0.0001058658,0.005544357],"genre_scores_gemma":[0.9739189,0.002030858,0.0007368841,0.0002552664,0.00004819045,0.00004501875,0.02234218,0.00002834054,0.0005943569],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01005843,"threshold_uncertainty_score":0.0227164,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02647245108970929,"score_gpt":0.3727301481313623,"score_spread":0.346257697041653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}