{"id":"W4409156463","doi":"10.1016/j.rbmo.2025.104980","title":"Proteomic signature of menstrual blood mesenchymal stromal cells and their extracellular vesicles in women with unexplained infertility","year":2025,"lang":"en","type":"article","venue":"Reproductive BioMedicine Online","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Cytodiagnostics (Canada)","funders":"European Regional Development Fund","keywords":"Extracellular vesicles; Unexplained infertility; Mesenchymal stem cell; Stromal cell; Microvesicles; Infertility; Andrology; Proteome; Endometriosis; Medicine; Cell biology; Biology; Physiology; Chemistry; Gynecology; Bioinformatics; Pregnancy; Internal medicine; Biochemistry; microRNA; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001330569,0.0001610103,0.0001997368,0.0006888536,0.00020204,0.0004019687,0.0001018796,0.0002881064,0.000844945],"category_scores_gemma":[0.0006361837,0.0000995852,0.0001929921,0.0003970488,0.0001552168,0.0001446624,0.0003321689,0.0001699166,0.000150104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009434523,"about_ca_system_score_gemma":0.000117379,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006382348,"about_ca_topic_score_gemma":0.0005571624,"domain_scores_codex":[0.9998955,0.00002020744,0.00001022957,0.00002141214,0.00002171124,0.00003098066],"domain_scores_gemma":[0.9999019,0.00002838891,0.00003089117,0.000004577837,0.00001622562,0.00001804413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004246345,0.00008815351,0.6901311,0.0004206811,0.0004337884,0.004428416,0.001373306,0.000334367,0.2492988,0.0004512148,0.001209286,0.04758459],"study_design_scores_gemma":[0.00002271902,0.0003299109,0.9746451,0.00006156477,0.0001699696,0.004880315,0.001247987,0.001048723,0.01359497,0.0002842123,0.003693073,0.00002140455],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966767,0.00199936,0.000199934,0.0000910798,0.00002280452,0.00001007759,0.0004501475,0.000006865671,0.0005430725],"genre_scores_gemma":[0.9981182,0.0007424952,0.0002359761,0.00006394818,0.00002390741,0.00001400736,0.0004046225,0.000003598905,0.0003931864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000844945,"threshold_uncertainty_score":0.002826631,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006266255741099323,"score_gpt":0.2242386674784285,"score_spread":0.2179724117373291,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}