{"id":"W4409165052","doi":"10.3390/vaccines13040389","title":"The Application of mRNA Technology for Vaccine Production—Current State of Knowledge","year":2025,"lang":"en","type":"review","venue":"Vaccines","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Production (economics); Current (fluid); State (computer science); Biochemical engineering; Computer science; Engineering; Electrical engineering; Economics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001531868,0.0008248389,0.001306924,0.002423267,0.0003146404,0.001522404,0.0009192922,0.001354947,0.002711364],"category_scores_gemma":[0.001500374,0.0004291534,0.0005671735,0.002066616,0.001169992,0.001725242,0.0007438124,0.001900354,0.00173231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008396048,"about_ca_system_score_gemma":0.001721272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001027775,"about_ca_topic_score_gemma":0.001034637,"domain_scores_codex":[0.9993734,0.0001380737,0.00008541238,0.0001011914,0.0002447483,0.00005731719],"domain_scores_gemma":[0.9986951,0.0009842393,0.00009813118,0.00003634509,0.0001502432,0.00003605575],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005530217,0.00006409496,0.0001526303,0.02631759,0.00004883841,0.0001898517,0.00008734513,0.0004824917,0.00490868,0.007831043,0.01372381,0.9461382],"study_design_scores_gemma":[0.00001115159,0.0001101355,0.000423743,0.004043545,0.00007217994,0.001102501,0.00006292693,0.000152908,0.003196891,0.003182561,0.9876167,0.00002473984],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001158391,0.9982262,0.0003427891,0.0002257476,0.0001510889,0.000003999901,0.000008668863,0.000006683273,0.0009189452],"genre_scores_gemma":[0.0007551415,0.9984125,0.0003149465,0.0001303567,0.0001418686,0.000006632323,0.00001326183,0.000002310756,0.0002228447],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002711364,"threshold_uncertainty_score":0.009070396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01798348453868477,"score_gpt":0.3397398995032491,"score_spread":0.3217564149645644,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}