{"id":"W4409175712","doi":"10.1016/j.cell.2025.03.003","title":"Genetically encoded reporters of actin filament organization in living cells and tissues","year":2025,"lang":"en","type":"article","venue":"Cell","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Fondation pour la Recherche Médicale; Agence Nationale de la Recherche; Canadian Institutes of Health Research; Fondation Bettencourt Schueller; Aix-Marseille Université","keywords":"Biology; Protein filament; Actin; Genetics; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003635083,0.0004053564,0.000297622,0.0004165288,0.0003504426,0.0007610165,0.0007260639,0.0007124185,0.001153263],"category_scores_gemma":[0.0003949278,0.0003478923,0.0003353799,0.0003453291,0.0007626702,0.0005215858,0.000533115,0.001527116,0.0004753245],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000636236,"about_ca_system_score_gemma":0.000326659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006226499,"about_ca_topic_score_gemma":0.001097808,"domain_scores_codex":[0.9997806,0.0000429919,0.00001517662,0.00004784946,0.00006842525,0.00004503991],"domain_scores_gemma":[0.9996734,0.00009828877,0.00008623723,0.00004277015,0.0000278754,0.00007146209],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006919999,0.00001763431,0.00005918272,0.00002467846,0.000002236084,0.00003538427,0.00002856359,0.0001450741,0.9958331,0.002650296,0.00006087318,0.001073772],"study_design_scores_gemma":[0.0000133268,0.00003292641,0.0003615271,0.000004203421,0.000005552529,0.00008567832,0.00002005851,0.001035845,0.9962034,0.0002338914,0.001998566,0.000005048649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8814416,0.002101295,0.1081987,0.000628417,0.0002740639,0.0001159981,0.001327062,0.0007064199,0.005206484],"genre_scores_gemma":[0.9471619,0.0009021407,0.0398797,0.0001178663,0.0000359476,0.0001083138,0.001113511,0.0002267322,0.01045407],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001153263,"threshold_uncertainty_score":0.004616201,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00393555014640665,"score_gpt":0.2225976175734096,"score_spread":0.218662067427003,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}