{"id":"W4409181656","doi":"10.1002/brb3.70308","title":"Multiplex Immunofluorescent Batch Labeling of Marmoset Brain Sections","year":2025,"lang":"en","type":"article","venue":"Brain and Behavior","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McGill University; Montreal Neurological Institute and Hospital","funders":"Fonds de Recherche du Québec - Santé; Multiple Sclerosis Society","keywords":"Marmoset; Callithrix; Biology; Immunolabeling; Neuroscience; Myelin; Multiplex; Computational biology; Immunohistochemistry; Bioinformatics; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001059954,0.0001024672,0.0001150826,0.00004414169,0.00008091138,0.00001583382,0.00008771976,0.0001179284,0.00001484608],"category_scores_gemma":[0.00005169092,0.00009997375,0.00006919609,0.00008122113,0.00007192085,0.000002083046,0.00004920873,0.00007363674,8.820328e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006984523,"about_ca_system_score_gemma":0.00004120287,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001567861,"about_ca_topic_score_gemma":0.0001271874,"domain_scores_codex":[0.9993951,0.00003349833,0.0001769179,0.000203274,0.00005476971,0.0001364556],"domain_scores_gemma":[0.9996846,0.0000220251,0.00003231887,0.0001756858,0.00004981804,0.00003557862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000429358,0.0001913624,0.01857863,0.00003116768,0.0000208822,0.000001234926,0.00004664209,0.000003043775,0.9683294,0.00004924665,0.002784737,0.009920733],"study_design_scores_gemma":[0.001618753,0.0002137735,0.08134359,0.00005784324,0.00008504175,0.000008871288,0.0001569106,0.0000684825,0.8828902,0.00002563466,0.03330434,0.000226579],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974895,0.0006678359,0.0005695651,0.0005475845,0.0002426191,0.0001732115,0.00004877268,0.0000115153,0.0002494622],"genre_scores_gemma":[0.9960175,0.0001054208,0.0009303034,0.000495851,0.00004907382,0.00002397492,0.00009600505,0.00001105481,0.002270808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08543921,"threshold_uncertainty_score":0.4076811,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009148153714544319,"score_gpt":0.2624148862896736,"score_spread":0.2532667325751293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}