{"id":"W4409193575","doi":"10.1002/imt2.70024","title":"Butyrate alleviates food allergy by improving intestinal barrier integrity through suppressing oxidative stress‐mediated Notch signaling","year":2025,"lang":"en","type":"article","venue":"iMeta","topic":"Food Allergy and Anaphylaxis Research","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fundamental Research Funds for the Central Universities; National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"Oxidative stress; Butyrate; Notch signaling pathway; Structural integrity; Medicine; Signal transduction; Chemistry; Cell biology; Biology; Food science; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004293914,0.0003616914,0.0005505765,0.0002116603,0.000298669,0.0001396159,0.0003531544,0.0002278541,0.0006052065],"category_scores_gemma":[0.001732162,0.0003019456,0.0001921895,0.0006075824,0.0002702524,0.0003303774,0.0002830041,0.001188341,0.00004625867],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009767756,"about_ca_system_score_gemma":0.0004183235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005011792,"about_ca_topic_score_gemma":0.0001341371,"domain_scores_codex":[0.9974581,0.0002126604,0.0005101716,0.0006457701,0.0004906398,0.000682652],"domain_scores_gemma":[0.998201,0.0005972447,0.0001375314,0.0004304681,0.0004226719,0.0002111584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004941683,0.0004006181,0.001401311,0.0002868174,0.001139277,0.00006543963,0.0005899551,0.00002044619,0.9822095,0.0005700144,0.004299192,0.008523252],"study_design_scores_gemma":[0.001949345,0.0008731587,0.0006670706,0.0007875827,0.000038496,0.00001263792,0.001230526,0.003231612,0.9744999,0.0008155828,0.01552021,0.0003738716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9656476,0.009323871,0.008464178,0.004203816,0.0003845376,0.0006898667,0.0002668031,0.0003236851,0.01069568],"genre_scores_gemma":[0.9922057,0.0001414028,0.003237005,0.0006555034,0.0001089115,0.00003786412,0.0002632856,0.00003969063,0.003310606],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02655817,"threshold_uncertainty_score":0.9999433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0267313615293445,"score_gpt":0.309969256225944,"score_spread":0.2832378946965994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}