{"id":"W4409204557","doi":"10.1080/2162402x.2025.2484880","title":"Surrogate markers of intestinal dysfunction associated with survival in advanced cancers","year":2025,"lang":"en","type":"article","venue":"OncoImmunology","topic":"Diet and metabolism studies","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"H2020 European Research Council; Bristol-Myers Squibb; Samsung; Institut Gustave-Roussy; Genentech; Ipsen; Daiichi Sankyo Europe; National Cancer Institute; Servier; Nordic Pharma Group; Eisai; F. Hoffmann-La Roche; Agence Nationale de la Recherche; Seagen; Seerave Foundation; Les Laboratories Pierre Fabre; AstraZeneca; Novocure; Taiho Pharmaceutical; Regeneron Pharmaceuticals; European Commission; Sanofi; Amgen; Pfizer; Celgene; Ignyta; Eli Lilly and Company","keywords":"Medicine; Oncology; Internal medicine; Surrogate endpoint; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004373951,0.0002472788,0.0003404032,0.0006697763,0.000254169,0.0005832132,0.0001538634,0.0002654557,0.001133171],"category_scores_gemma":[0.001080605,0.00007935364,0.0002303257,0.001002006,0.0001712643,0.0001974832,0.0004345694,0.0003872983,0.0001676128],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002140212,"about_ca_system_score_gemma":0.0001449288,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007397193,"about_ca_topic_score_gemma":0.001402658,"domain_scores_codex":[0.9997641,0.00008578504,0.00002660638,0.00005349075,0.00003292808,0.00003706539],"domain_scores_gemma":[0.9991552,0.0001203885,0.0004308217,0.00005871573,0.0000819711,0.0001529212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009020061,0.00003896585,0.990422,0.00006155037,0.0001007686,0.00005166435,0.00005397513,0.000102177,0.003142809,0.00004091877,0.0001616263,0.004921575],"study_design_scores_gemma":[0.000005394115,0.0003061378,0.9978636,0.00001057717,0.00006405612,0.0001701067,0.00008784857,0.0001777912,0.0006267186,0.00006686329,0.000617275,0.000003705812],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946626,0.002522171,0.0003652263,0.00006797294,0.00002002394,0.00001409997,0.001254242,0.00001463192,0.001078947],"genre_scores_gemma":[0.9984623,0.0003364242,0.0002056969,0.00002916245,0.00001344492,0.00001230429,0.000693114,0.000002332316,0.0002453607],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001133171,"threshold_uncertainty_score":0.003790855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01095478614241044,"score_gpt":0.2691212604981573,"score_spread":0.2581664743557468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}