{"id":"W4409211631","doi":"10.1007/s13205-025-04280-y","title":"Protective effects of ascorbic acid against anticancer drug-induced oxidative stress and genotoxic damage in Saccharomyces cerevisiae","year":2025,"lang":"en","type":"article","venue":"3 Biotech","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Innovation Cluster (Canada)","funders":"","keywords":"Oxidative stress; Ascorbic acid; Saccharomyces cerevisiae; Drug; Oxidative damage; Chemistry; Pharmacology; DNA damage; Genotoxicity; Biochemistry; Biology; Toxicity; Yeast; Food science; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001283555,0.0002406877,0.0003387475,0.0001340765,0.00005261267,0.00001986149,0.0002472574,0.0002326689,0.000003783246],"category_scores_gemma":[0.0001854769,0.0002325013,0.00006954487,0.0002373854,0.0001834937,0.000007900238,0.0002400669,0.0002181703,0.000001541535],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003563795,"about_ca_system_score_gemma":0.00009446529,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007178498,"about_ca_topic_score_gemma":0.0001508,"domain_scores_codex":[0.9986979,0.0001133666,0.0002728448,0.000542469,0.00009831054,0.0002751362],"domain_scores_gemma":[0.999311,0.00004145496,0.0001377563,0.0003701,0.00008411875,0.00005562537],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000788948,0.00009766033,0.004488287,0.0003884943,0.00008300009,0.000003556217,0.0001607942,0.000002914599,0.9901774,0.0000690553,0.0000403031,0.004409637],"study_design_scores_gemma":[0.000862391,0.000125847,0.03782397,0.0003231089,0.0000196767,4.051536e-7,0.0001845046,0.00001528,0.9600248,0.0002529084,0.0001548427,0.0002123134],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956661,0.002292415,0.0003333657,0.0001196914,0.00009044541,0.0008894094,0.00004898084,0.00001124877,0.000548323],"genre_scores_gemma":[0.9986987,0.000576779,0.0003555997,0.0001081286,0.00005571462,0.00008810995,0.00003915891,0.00001793058,0.0000598996],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03333568,"threshold_uncertainty_score":0.9481128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004457382464071994,"score_gpt":0.2432673238735266,"score_spread":0.2388099414094547,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}