{"id":"W4409212664","doi":"10.13107/jocr.2025.v15.i04.5520","title":"Cartilage Regeneration Potential of Platelet-Rich Plasma versus Plasma Rich in Growth Factors in Knee Osteoarthritis Based on Serum Biomarker of Cartilage Degradation, Coll2-1: A Triple-Blind Randomized Study","year":2025,"lang":"en","type":"article","venue":"Journal of Orthopaedic Case Reports","topic":"Periodontal Regeneration and Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Osteoarthritis; Platelet-rich plasma; WOMAC; Biomarker; Cartilage; Randomized controlled trial; Internal medicine; Articular cartilage; Cartilage damage; Gastroenterology; Platelet; Pathology; Anatomy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001636053,0.000302321,0.00136374,0.001612685,0.00007463503,0.00002713718,0.00004321999,0.0001865459,0.0000591621],"category_scores_gemma":[0.001596823,0.0002433667,0.0003924539,0.001130359,0.0000935974,0.0001956353,0.00002585651,0.000274031,3.58633e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003288002,"about_ca_system_score_gemma":0.0009487396,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002141887,"about_ca_topic_score_gemma":0.002649686,"domain_scores_codex":[0.995468,0.0004657742,0.002602286,0.0003302351,0.0008883293,0.0002453881],"domain_scores_gemma":[0.9971646,0.0002957063,0.001509817,0.0003100221,0.000554583,0.0001652397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.2927072,0.005227766,0.4440298,0.0002515008,0.000664028,0.222703,0.001280099,0.002576647,0.0262237,0.00001658993,0.0002119318,0.004107705],"study_design_scores_gemma":[0.6876466,0.005213556,0.06997681,0.0008790152,0.00129906,0.01064186,0.001823142,0.003042089,0.2190962,0.000009646331,0.00003506823,0.0003369369],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961116,0.000230874,0.00006125598,0.0001385701,0.001374354,0.001793137,0.00002458029,0.000009782339,0.0002558059],"genre_scores_gemma":[0.9993351,0.00003303103,0.0001374542,0.00001916626,0.00004268377,0.0000463603,0.00005614564,0.00002179956,0.0003082943],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3949394,"threshold_uncertainty_score":0.9924204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01843469065433262,"score_gpt":0.2810111015967636,"score_spread":0.2625764109424309,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}