{"id":"W4409220815","doi":"10.1093/synbio/ysaf008","title":"Engineering a custom-sized DNA scaffold for more efficient DNA origami-based nucleic acid data storage","year":2025,"lang":"en","type":"article","venue":"Synthetic Biology","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"Boise State University; National Science Foundation","keywords":"Nucleic acid; DNA origami; DNA; Scaffold; Computer science; Nanotechnology; Chemistry; Materials science; Biochemistry; Database","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004046469,0.0002829296,0.0003630589,0.000156237,0.000116351,0.00002000069,0.0005888304,0.0003667101,0.000004741303],"category_scores_gemma":[0.0004014361,0.0002394898,0.0001682699,0.0002168605,0.0002302118,0.000002448556,0.0002859813,0.0001044012,0.00000369842],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003542851,"about_ca_system_score_gemma":0.0001228985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005837575,"about_ca_topic_score_gemma":0.000009370573,"domain_scores_codex":[0.9982677,0.00006740156,0.0003169965,0.0008494261,0.00007100165,0.0004274916],"domain_scores_gemma":[0.9983779,0.00006794067,0.0001093228,0.001275224,0.0001011898,0.00006842295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001293129,0.00008912459,0.00004610295,0.00004660267,0.0001125178,0.000001719739,0.000004727646,0.0001409255,0.9941188,0.0003311278,0.0008285046,0.004150541],"study_design_scores_gemma":[0.0006469247,0.0001540701,0.00005128564,0.00006714386,0.0001281955,0.000005744128,0.00002646721,0.02315073,0.9048672,0.00006935491,0.07051186,0.0003210159],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7649338,0.001075286,0.2294666,0.001994339,0.0005558875,0.00081818,0.0005887802,0.0002713849,0.0002957552],"genre_scores_gemma":[0.9837626,0.00003165196,0.01460257,0.0004434239,0.0001153427,0.00004647337,0.0007737625,0.00003048889,0.0001936722],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2188288,"threshold_uncertainty_score":0.9766111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01134563588859739,"score_gpt":0.2854828494580622,"score_spread":0.2741372135694648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}