{"id":"W4409222014","doi":"10.1161/atvb.39.suppl_1.407","title":"Abstract 407: Apabetalone (RVX-208) Inhibits Key Pro-Atherogenic Mediators and Pathways in Diabetes and Inflammatory Conditions; <i>in vitro</i> and in Patients","year":2019,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Resverlogix (Canada)","funders":"","keywords":"Diabetes mellitus; In vitro; Medicine; Inflammation; Internal medicine; Endocrinology; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001425374,0.0005176623,0.0003561071,0.0002187491,0.0001157189,0.0002859904,0.0001592722,0.0002858494,0.005670927],"category_scores_gemma":[0.0001020321,0.00009872609,0.0002787705,0.0001629383,0.00012158,0.0001120797,0.0001118757,0.0007845811,0.001244364],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000174447,"about_ca_system_score_gemma":0.0002560513,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004879553,"about_ca_topic_score_gemma":0.0007690613,"domain_scores_codex":[0.9999294,0.00001444177,0.000007265422,0.00001061886,0.0000159246,0.00002225122],"domain_scores_gemma":[0.9999505,0.000007007829,0.00001157802,0.000003289745,0.000006568672,0.00002104223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01723569,0.002288667,0.002428738,0.0008637003,0.000167881,0.0003950055,0.00003728731,0.0003918045,0.8967089,0.0003200981,0.005936638,0.07322552],"study_design_scores_gemma":[0.006678158,0.0534327,0.04571678,0.0001592038,0.000505385,0.002109437,0.00007847218,0.001468374,0.8463435,0.0002895061,0.04318899,0.00002950654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9535335,0.02703106,0.00208792,0.001112807,0.0005768167,0.0002800453,0.003534911,0.0004402543,0.01140283],"genre_scores_gemma":[0.9726422,0.01092422,0.001893771,0.0008545486,0.0002535621,0.0001889798,0.003808699,0.00003544411,0.009398656],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005670927,"threshold_uncertainty_score":0.01897115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009281041048826728,"score_gpt":0.2031075247487474,"score_spread":0.1938264836999206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}