{"id":"W4409255937","doi":"10.1016/bs.ircmb.2025.03.002","title":"Interleukin-33: A new frontier in cancer immunotherapy","year":2025,"lang":"en","type":"book-chapter","venue":"International review of cell and molecular biology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Institute for Cancer Research, Keimyung University; Fraser Institute; Canadian Institutes of Health Research; University of Queensland; Canadian Cancer Society; Cumming School of Medicine, University of Calgary; University of Calgary; Australian Government; Alberta Cancer Foundation; Cancer Research Society; Cancer Council NSW; National Health and Medical Research Council; Arnie Charbonneau Cancer Institute, University of Calgary","keywords":"Biology; Immunotherapy; Cancer immunotherapy; Frontier; Cancer; Immunology; Interleukin 15; Cancer research; Interleukin; Cytokine; Immune system; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001559068,0.0003326141,0.0007992032,0.0002466177,0.00001758377,0.00000509962,0.0004059371,0.0005072616,0.0009496379],"category_scores_gemma":[0.00004899715,0.000287942,0.0002448225,0.00003366872,0.0001883807,0.00002380413,0.000157627,0.0004058069,0.00004557436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000656624,"about_ca_system_score_gemma":0.0003397426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002293566,"about_ca_topic_score_gemma":0.00005567592,"domain_scores_codex":[0.9985955,0.00007716341,0.0006477568,0.0004277365,0.00004352855,0.0002082818],"domain_scores_gemma":[0.9991556,0.00005829963,0.000351024,0.0002571811,0.0001564397,0.00002139413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004375818,0.000176553,0.0002232846,0.004286925,0.00211535,0.00006266891,0.0002271633,4.720966e-7,0.4013906,0.2507281,0.0673461,0.2730052],"study_design_scores_gemma":[0.0008452375,0.0001238621,0.00001936241,0.005175595,0.00007143967,0.00001626722,0.000003252784,3.229806e-7,0.01270536,0.006045221,0.9747553,0.0002387705],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004173168,0.6509289,0.001101776,0.0007599206,0.002358208,0.0005199348,0.001773394,0.00002712822,0.3421134],"genre_scores_gemma":[0.003747295,0.647842,0.0002472315,0.004325578,0.00008282931,0.00004176581,0.0009355065,0.00004716431,0.3427306],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9074092,"threshold_uncertainty_score":0.9999636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008715281310847306,"score_gpt":0.2748627150565083,"score_spread":0.266147433745661,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}