{"id":"W4409263339","doi":"10.1021/acs.cgd.5c00089","title":"Hiding in Plain Sight: Polymorphs of Riluzole","year":2025,"lang":"en","type":"article","venue":"Crystal Growth & Design","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Canada Foundation for Innovation; Centre québécois sur les matériaux fonctionnels","keywords":"Riluzole; Sight; Medicine; Chemistry; Stereochemistry; Internal medicine; Physics; Optics; Amyotrophic lateral sclerosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001335165,0.0001317336,0.0002432825,0.0002552455,0.0003829008,0.0008537759,0.0003288848,0.0003245531,0.003562663],"category_scores_gemma":[0.0006005965,0.0001632152,0.0001744618,0.0004524073,0.0005080587,0.001209175,0.0004916617,0.0006869952,0.0007219088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003201032,"about_ca_system_score_gemma":0.0001820704,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006739451,"about_ca_topic_score_gemma":0.000972491,"domain_scores_codex":[0.9998356,0.00002459464,0.00001067963,0.00003942077,0.00006018935,0.00002947739],"domain_scores_gemma":[0.9998662,0.00002744693,0.00003351356,0.0000323018,0.00002353534,0.00001695664],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001889794,0.0002399517,0.01142638,0.0006510822,0.00008312471,0.003084627,0.001491015,0.004333207,0.6557565,0.08566838,0.03019331,0.2051827],"study_design_scores_gemma":[0.0003986578,0.001209895,0.02400656,0.0002278539,0.0001449111,0.009077346,0.002979817,0.03104847,0.4047814,0.09544049,0.4304721,0.0002124511],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9048408,0.01158276,0.02585411,0.005876506,0.0004354231,0.00006015558,0.001543052,0.0005282002,0.04927896],"genre_scores_gemma":[0.9764853,0.003211433,0.01093004,0.0007607793,0.00009506001,0.00003029721,0.0007052793,0.0001794446,0.007602303],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003562663,"threshold_uncertainty_score":0.01191831,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008655029238035,"score_gpt":0.2277696244745154,"score_spread":0.2191145952364804,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}