{"id":"W4409263339","doi":"10.1021/acs.cgd.5c00089","title":"Hiding in Plain Sight: Polymorphs of Riluzole","year":2025,"lang":"en","type":"article","venue":"Crystal Growth & Design","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Canada Foundation for Innovation; Centre québécois sur les matériaux fonctionnels","keywords":"Riluzole; Sight; Medicine; Chemistry; Stereochemistry; Internal medicine; Physics; Optics; Amyotrophic lateral sclerosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001876983,0.0001103204,0.0001904074,0.00008551371,0.00002899563,0.00001103967,0.0001638984,0.0001115038,0.00003292959],"category_scores_gemma":[0.0001524221,0.0001026362,0.0001126441,0.0002472324,0.00005542242,0.000002769241,0.00007441526,0.00005543106,0.000001813604],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001598268,"about_ca_system_score_gemma":0.00004663853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004552771,"about_ca_topic_score_gemma":0.000007830936,"domain_scores_codex":[0.9992035,0.00006479852,0.0002368034,0.0002384873,0.00007953536,0.0001768605],"domain_scores_gemma":[0.9996517,0.00004685005,0.00005483365,0.0001737842,0.00003393746,0.00003887583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006007614,0.00006020791,0.002918675,0.00002566531,0.00004096886,0.000002718232,0.00001466695,0.00003369695,0.9947817,0.0003188233,0.0009136928,0.0008291203],"study_design_scores_gemma":[0.000271925,0.00003583228,0.0007901549,0.0000442929,0.00002459266,9.183759e-7,0.00004154332,0.0001917973,0.9963939,0.0006948678,0.001399274,0.0001109024],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9472049,0.001804451,0.04361182,0.0002737013,0.00004916884,0.000155339,0.00001224952,0.00001220129,0.006876179],"genre_scores_gemma":[0.9984583,0.00005400112,0.000737237,0.00008433417,0.00003759073,0.00001034975,0.00001519421,0.000008752232,0.0005942486],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05125341,"threshold_uncertainty_score":0.4185382,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008655029238035,"score_gpt":0.2277696244745154,"score_spread":0.2191145952364804,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}