{"id":"W4409315342","doi":"10.1093/ofid/ofaf212","title":"Toward Personalized Medicine: The Effect of Treatment of Chronic Enterovirus Diarrhea in an Immunocompromised Patient and the Correlation With In Vitro Models","year":2025,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"European Commission; Amsterdam University Medical Centers; Health~Holland","keywords":"Medicine; Diarrhea; Correlation; Enterovirus; Personalized medicine; In vitro; Intensive care medicine; Immunology; Virology; Internal medicine; Bioinformatics; Virus; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008005877,0.0003037103,0.0005210603,0.0002816342,0.0001570795,0.0008202763,0.0002992121,0.0006127236,0.001584501],"category_scores_gemma":[0.001172277,0.00008847647,0.0004439532,0.0002699868,0.000197052,0.0004593267,0.000331069,0.0008132848,0.0003897179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003449206,"about_ca_system_score_gemma":0.0002371048,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003254991,"about_ca_topic_score_gemma":0.0005984714,"domain_scores_codex":[0.9994317,0.0003600131,0.00002895813,0.00006016124,0.00008595227,0.00003330585],"domain_scores_gemma":[0.9994838,0.0002200262,0.0001101261,0.00007668424,0.00006856052,0.00004086504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002858426,0.001409621,0.04169883,0.004079183,0.0008319736,0.002785921,0.0004412142,0.007690027,0.09962174,0.006555731,0.01628545,0.8157418],"study_design_scores_gemma":[0.0008788437,0.02457934,0.1729263,0.003429434,0.00397045,0.03340516,0.001379848,0.03368607,0.1951772,0.02605069,0.504266,0.0002506513],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4894657,0.416716,0.03524774,0.02244179,0.001176845,0.0002233755,0.00153931,0.0004696311,0.03271966],"genre_scores_gemma":[0.8843635,0.08943494,0.0169677,0.004664118,0.000943914,0.0001261706,0.0009346766,0.00004915689,0.002515856],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001584501,"threshold_uncertainty_score":0.005300701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01362607104788391,"score_gpt":0.3067575475784747,"score_spread":0.2931314765305909,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}