{"id":"W4409348630","doi":"10.7554/elife.104268.2","title":"Wag31, a membrane tether, is crucial for lipid homeostasis in mycobacteria","year":2025,"lang":"en","type":"preprint","venue":"eLife","topic":"Mycobacterium research and diagnosis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Science and Engineering Research Board; National Institutes of Health; Indian Institute of Science Education and Research Mohali; University of Hyderabad; Canadian Institutes of Health Research; Mitacs; Innovation Saskatchewan; University of Saskatchewan; Council of Scientific and Industrial Research, India; Department of Biotechnology, Ministry of Science and Technology, India; Indian Institute of Science","keywords":"Homeostasis; Membrane; Chemistry; Cell biology; Lipid accumulation; Biophysics; Microbiology; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000724172,0.0003084204,0.0001752648,0.0001806729,0.0002657826,0.0002658493,0.000146714,0.0004742779,0.0003607771],"category_scores_gemma":[0.0001327114,0.0001217567,0.0001655187,0.0001572796,0.0001840052,0.0002415338,0.0003325919,0.0002827168,0.0004031252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001866688,"about_ca_system_score_gemma":0.00009748849,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003017563,"about_ca_topic_score_gemma":0.0004625745,"domain_scores_codex":[0.9999305,0.0000108577,0.000007697263,0.0000172611,0.00001929872,0.00001431129],"domain_scores_gemma":[0.9998969,0.00001214846,0.00003674312,0.00001405767,0.00001102809,0.00002905645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001884406,0.000002741124,0.0003285543,0.00001197508,0.00000117119,0.00007177049,0.000005969838,0.00002873258,0.9991228,0.00003501675,0.00001194261,0.0003604406],"study_design_scores_gemma":[0.0000103559,0.0001109612,0.02777718,0.00001453984,0.00001391368,0.0008904765,0.00006152637,0.003002013,0.965129,0.0002072218,0.002775074,0.000007700356],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961438,0.00109073,0.002122578,0.00006267799,0.00001064842,0.000008037463,0.0001412016,0.00006354753,0.0003567089],"genre_scores_gemma":[0.9982409,0.0001605674,0.0009683926,0.00002340114,0.000002125236,0.000006004646,0.0002061123,0.000008100727,0.0003843254],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004742779,"threshold_uncertainty_score":0.001354396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04243940621544159,"score_gpt":0.3604924210173637,"score_spread":0.3180530148019222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}