{"id":"W4409362115","doi":"10.58931/cot.2025.2134","title":"Advances in Adjuvant Therapy for High-Risk Breast Cancer: A Canadian Clinical Approach","year":2025,"lang":"en","type":"article","venue":"Canadian oncology today.","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"Breast cancer; Adjuvant therapy; Medicine; Oncology; Adjuvant; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003030906,0.000240199,0.0004319665,0.0002497551,0.0002285504,0.00001295104,0.0002871578,0.0004111688,0.00003601165],"category_scores_gemma":[0.0000795497,0.0002311531,0.0001158305,0.0002243147,0.0002260575,0.00000733284,0.00003077364,0.000194829,0.00000421082],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009774492,"about_ca_system_score_gemma":0.006572753,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.8011976,"about_ca_topic_score_gemma":0.9953799,"domain_scores_codex":[0.9981255,0.0001446005,0.0003446444,0.0006237171,0.00004934125,0.0007122195],"domain_scores_gemma":[0.998946,0.00006996177,0.00009292416,0.0003371967,0.0001207345,0.000433227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003568302,0.0001097393,0.4889355,0.00001488655,0.0002122458,0.00001640416,0.00006757712,0.00007508522,0.00002419948,0.000740635,0.02185134,0.4875956],"study_design_scores_gemma":[0.003337235,0.0002437192,0.4255906,0.00002474906,0.00004923372,0.00001202872,0.0001844627,0.00002420118,0.00009256972,0.0004037791,0.5697889,0.0002484734],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7795313,0.09691118,0.0006079538,0.04917382,0.005839668,0.00449305,0.00964938,0.00006576742,0.05372787],"genre_scores_gemma":[0.9756716,0.0169052,0.0005723852,0.004883686,0.0004058425,0.0008772923,0.0002704283,0.00002676323,0.0003867665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5479376,"threshold_uncertainty_score":0.9990591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01188623016764734,"score_gpt":0.3271848254345535,"score_spread":0.3152985952669062,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}