{"id":"W4409411623","doi":"10.1128/jb.00024-25","title":"Defining the networks that connect RNase III and RNase J-mediated regulation of primary and specialized metabolism in <i>Streptomyces venezuelae</i>","year":2025,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"RNase P; Regulon; Biology; RNase MRP; RNA; Non-coding RNA; Gene expression; Cell biology; Biochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000086301,0.0001952068,0.0001315784,0.0002519428,0.0002270382,0.0003430406,0.0001087641,0.0001326061,0.0007112961],"category_scores_gemma":[0.0001186663,0.000110942,0.0001365872,0.0001986409,0.0002046596,0.0001714105,0.0001851096,0.0001873235,0.0001302306],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000426373,"about_ca_system_score_gemma":0.0002526211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003056028,"about_ca_topic_score_gemma":0.004082262,"domain_scores_codex":[0.9999491,0.000006261266,0.000002200806,0.00002151733,0.000005214906,0.00001576364],"domain_scores_gemma":[0.9998932,0.00001868002,0.00004528145,0.000007450673,0.00001356436,0.00002177506],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001271805,0.00001191226,0.0058772,0.00004754338,0.000005626746,0.0001021878,0.00004125933,0.0005969277,0.9903207,0.00033332,0.00006856695,0.002467537],"study_design_scores_gemma":[0.00003612764,0.0004589494,0.6256811,0.00005596749,0.00006421596,0.0005756504,0.0006350654,0.01796521,0.3435759,0.002565169,0.008353783,0.0000328222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948361,0.0006873257,0.002706244,0.0000645302,0.000007054278,0.0000103136,0.0004155914,0.00009799973,0.001174944],"genre_scores_gemma":[0.9973745,0.000151583,0.001291372,0.00002365107,0.000004046615,0.000009099206,0.0004748225,0.000007404166,0.000663484],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003056028,"threshold_uncertainty_score":0.006076455,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006441238683662358,"score_gpt":0.2216151107534066,"score_spread":0.2151738720697443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}