{"id":"W4409411967","doi":"10.1016/j.jare.2025.04.016","title":"Bacteroides thetaiotaomicron: A symbiotic ally against diarrhea along with modulation of gut microbial ecological networks via tryptophan metabolism and AHR-Nrf2 signaling","year":2025,"lang":"en","type":"article","venue":"Journal of Advanced Research","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Beijing Institute of Genomics, Chinese Academy of Sciences; Sichuan Province Science and Technology Support Program; Natural Science Foundation of Sichuan Province; University of British Columbia; National Natural Science Foundation of China","keywords":"Bacteroides thetaiotaomicron; Metabolism; Chemistry; Microbiology; Tryptophan; Diarrhea; Bacteroides; Biology; Cell biology; Biochemistry; Bacteria; Medicine; Internal medicine; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003390573,0.0005776354,0.0004546175,0.0002804633,0.0002521918,0.0003959951,0.0002084641,0.000499333,0.001706107],"category_scores_gemma":[0.0001438939,0.0001523652,0.0005008065,0.0001473552,0.000278418,0.0003730518,0.000526724,0.0007327152,0.0003123429],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002471068,"about_ca_system_score_gemma":0.0005624619,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005569774,"about_ca_topic_score_gemma":0.001050862,"domain_scores_codex":[0.9998208,0.00003871606,0.00001305793,0.0000437907,0.0000348099,0.00004880954],"domain_scores_gemma":[0.9998847,0.000007212727,0.00003296275,0.000007484601,0.00002210635,0.00004544199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006793432,0.00008424326,0.001023199,0.0004448175,0.00002971606,0.0001165185,0.00004976599,0.00004158484,0.9904628,0.0000894642,0.0001833396,0.006795082],"study_design_scores_gemma":[0.0003239943,0.00979725,0.08949508,0.0003579315,0.0004839776,0.001171961,0.0008494535,0.001403531,0.8519195,0.0008499793,0.04326363,0.00008382669],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9669881,0.01812449,0.008666407,0.0015451,0.0004409136,0.0001436752,0.0008032644,0.0002600569,0.00302807],"genre_scores_gemma":[0.9840723,0.005628813,0.004850392,0.000631007,0.00006279188,0.0001337372,0.0005722917,0.00002963191,0.004019067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001706107,"threshold_uncertainty_score":0.005707443,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01203584661686724,"score_gpt":0.3055151063410403,"score_spread":0.293479259724173,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}