{"id":"W4409414530","doi":"10.1159/000543754","title":"Microbiome Maturation Trajectory and Key Milestones in Early Life","year":2025,"lang":"en","type":"review","venue":"Annals of Nutrition and Metabolism","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Microbiome; Biology; Psychological intervention; Dysbiosis; Breastfeeding; Window of opportunity; Physiology; Medicine; Bioinformatics; Pediatrics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005205654,0.0005399262,0.0007410541,0.0007846533,0.0001725204,0.0007897098,0.0004274902,0.0007806471,0.002551445],"category_scores_gemma":[0.00135788,0.0001241544,0.0004808421,0.0005535444,0.000286648,0.0006479374,0.0005618056,0.0009459475,0.0007285408],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004814514,"about_ca_system_score_gemma":0.001083059,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001454013,"about_ca_topic_score_gemma":0.001776102,"domain_scores_codex":[0.9998038,0.00005736556,0.00002358384,0.00004367061,0.00004734056,0.00002424496],"domain_scores_gemma":[0.9996539,0.0001645043,0.00007382325,0.000006086997,0.00006936045,0.00003240656],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002812133,0.00004684412,0.00257564,0.021108,0.0001882762,0.0003207727,0.0002091227,0.000322254,0.001664662,0.004333082,0.01429905,0.9546511],"study_design_scores_gemma":[0.00003188168,0.0004429873,0.02784409,0.03075009,0.000567694,0.005480289,0.0004916785,0.0002894187,0.002076534,0.005845953,0.9261078,0.00007157387],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008490362,0.9971598,0.0002414435,0.0005573593,0.0001902947,0.000007805301,0.00007024484,0.000009163083,0.0009147921],"genre_scores_gemma":[0.005872499,0.992837,0.0003823074,0.0001786689,0.0001384144,0.00001366442,0.00009025427,0.000002409943,0.0004847647],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002551445,"threshold_uncertainty_score":0.008535385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04420488491816945,"score_gpt":0.3481409082865099,"score_spread":0.3039360233683405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}