{"id":"W4409465384","doi":"10.3310/fwxv5380","title":"The clinical utility and safety of biomarker-guided immunosuppression withdrawal in liver transplantation: the LIFT prospective RCT","year":2025,"lang":"en","type":"article","venue":"Efficacy and Mechanism Evaluation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Efficacy and Mechanism Evaluation Programme","keywords":"Immunosuppression; Randomized controlled trial; Medicine; Liver transplantation; Transplantation; Biomarker; Intensive care medicine; Internal medicine; Oncology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02241993,0.001574207,0.002938884,0.0006965217,0.0005554873,0.001830108,0.0008837773,0.002924716,0.004502146],"category_scores_gemma":[0.04505135,0.0005677473,0.005363769,0.0008679227,0.00164763,0.002333488,0.001571203,0.002000551,0.000531182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008936521,"about_ca_system_score_gemma":0.001540006,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001022895,"about_ca_topic_score_gemma":0.001023116,"domain_scores_codex":[0.9699041,0.02511191,0.002031475,0.001553685,0.0008194658,0.0005794853],"domain_scores_gemma":[0.9646399,0.02152241,0.008281319,0.002715165,0.001588155,0.001253014],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.858533,0.00164552,0.0526785,0.01392424,0.02930067,0.0002196434,0.000484439,0.0006274401,0.001202447,0.001009203,0.001523239,0.03885168],"study_design_scores_gemma":[0.7126955,0.1136415,0.08648752,0.005547381,0.06571978,0.0003873391,0.0007188646,0.003344469,0.001144962,0.003552156,0.006582947,0.0001776937],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.924277,0.05265259,0.004070382,0.002920398,0.001293511,0.009594712,0.001493852,0.000109317,0.003588248],"genre_scores_gemma":[0.9870301,0.002688282,0.002545253,0.001035355,0.0003377975,0.005345161,0.0003907299,0.00001310843,0.000614145],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02241993,"threshold_uncertainty_score":0.1185693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05081033371812584,"score_gpt":0.3892460145924387,"score_spread":0.3384356808743129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}