{"id":"W4409490318","doi":"10.1016/s1474-4422(25)00103-6","title":"CGRP blockade and cluster headache: another step forward","year":2025,"lang":"en","type":"article","venue":"The Lancet Neurology","topic":"Migraine and Headache Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"Cluster headache; Blockade; Calcitonin gene-related peptide; Cluster (spacecraft); Medicine; Computer science; Internal medicine; Migraine; Computer network; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001903004,0.0001057355,0.0003574771,0.0000458339,0.00009020472,0.000006458401,0.00008512674,0.00007316322,0.00005148016],"category_scores_gemma":[0.00007627633,0.00006361244,0.00004628534,0.00009340803,0.0001634074,0.00001227141,0.0001124105,0.0002912241,0.00002011081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003888442,"about_ca_system_score_gemma":0.00002300273,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004970923,"about_ca_topic_score_gemma":0.0001903557,"domain_scores_codex":[0.9992788,0.000084026,0.0001268383,0.0001870321,0.00005912039,0.0002642207],"domain_scores_gemma":[0.9994261,0.0001889163,0.00002568348,0.0003118947,0.00002330803,0.00002409677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001325187,0.00005655989,0.1135148,0.0001418118,0.0002033517,0.00003162907,0.0006501496,0.000001791966,0.001337666,0.003033618,0.8768848,0.002818664],"study_design_scores_gemma":[0.002156461,0.0003401547,0.1865547,0.00001569144,0.0001321118,0.00009894107,0.00004641614,0.0002585835,0.0001769848,0.001063531,0.8090876,0.00006875524],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5719631,0.00229451,0.0002225299,0.3766139,0.0000656303,0.0003314775,0.000004147019,0.0000722888,0.04843235],"genre_scores_gemma":[0.8637172,0.0004241851,0.0001299317,0.115717,0.0004823051,0.00002525991,0.000001871178,0.00001258682,0.01948971],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2917541,"threshold_uncertainty_score":0.259404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02463699265385246,"score_gpt":0.3041562444962759,"score_spread":0.2795192518424234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}