{"id":"W4409523192","doi":"10.1038/s41564-025-01998-6","title":"Dairy cows develop protective immunity against reinfection with bovine H5N1 influenza virus","year":2025,"lang":"en","type":"article","venue":"Nature Microbiology","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; Canadian Science Centre for Human and Animal Health; Health Sciences Centre; University of Toronto; Sinai Health System; Sunnybrook Health Science Centre; Shared Health; University of Saskatchewan","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada; Innovation Saskatchewan; U.S. Department of Agriculture","keywords":"Influenza A virus subtype H5N1; Virology; Immunity; Virus; Biology; H5N1 genetic structure; Influenza A virus; Immunology; Immune system; Medicine; Coronavirus disease 2019 (COVID-19); Internal medicine; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000477707,0.0002394711,0.0005712145,0.0003036309,0.0001667524,0.000009767778,0.0001600694,0.0007309195,0.00005343327],"category_scores_gemma":[0.001265639,0.0001751497,0.0000775252,0.0005425781,0.0003482485,0.00005944819,0.000160158,0.002218439,0.00004530551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002666395,"about_ca_system_score_gemma":0.0003549161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001761247,"about_ca_topic_score_gemma":0.0006010413,"domain_scores_codex":[0.9981614,0.0004506095,0.0003302743,0.0004289517,0.00005229551,0.0005765166],"domain_scores_gemma":[0.9989225,0.00006612269,0.0001021141,0.0003566969,0.0004501829,0.0001023608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.005941092,0.0001694999,0.02795726,0.0001385393,0.0003832437,0.0001004733,0.00005472807,0.000008640204,0.943059,0.0001851743,0.01488602,0.007116312],"study_design_scores_gemma":[0.01285655,0.008004558,0.260987,0.001012321,0.0001630578,0.002001819,0.000196848,0.00006296748,0.1276164,0.0004336272,0.5860351,0.0006298011],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902781,0.001431616,0.001455989,0.00245652,0.0002926952,0.001008729,0.00005844889,0.0001300348,0.002887838],"genre_scores_gemma":[0.9852025,0.0001362178,0.001565124,0.01182926,0.0001133876,0.000100313,0.0003583862,0.00002000823,0.0006748246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8154426,"threshold_uncertainty_score":0.9638137,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01087409769229669,"score_gpt":0.3076200179613032,"score_spread":0.2967459202690065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}