{"id":"W4409525903","doi":"10.1016/j.celrep.2025.115571","title":"Bacterial pneumonia induces senescence in resident alveolar macrophages that are outcompeted by monocytes","year":2025,"lang":"en","type":"article","venue":"Cell Reports","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Zhejiang University; Natural Science Foundation of Zhejiang Province; National Natural Science Foundation of China; Shandong First Medical University; McMaster University","keywords":"Senescence; Pneumonia; Microbiology; Monocyte; Biology; Bacteria; Macrophage; Immunology; Chemistry; Cell biology; Medicine; Biochemistry; Internal medicine; In vitro; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002671418,0.0002367555,0.0003177859,0.0003154555,0.0001031434,0.0003241264,0.0001151048,0.0003001813,0.0008742173],"category_scores_gemma":[0.0002046247,0.0001653867,0.0002486852,0.0001415971,0.0001556248,0.0001745227,0.0002485856,0.0004806489,0.0004821063],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001274411,"about_ca_system_score_gemma":0.0001542304,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002099912,"about_ca_topic_score_gemma":0.0003030009,"domain_scores_codex":[0.9996526,0.00007984059,0.00003231372,0.00004037609,0.00007593229,0.0001189845],"domain_scores_gemma":[0.9997199,0.00005729531,0.00005866572,0.00003658583,0.00003703626,0.00009053835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003047361,0.00003980898,0.0009203261,0.00003126145,0.000004520636,0.0001747071,0.0000261257,0.00002020928,0.9967155,0.00006076696,0.0000484984,0.001653458],"study_design_scores_gemma":[0.00009851686,0.002826313,0.09879243,0.00003596101,0.00004162723,0.002597252,0.0002157243,0.001741694,0.8883247,0.0002791453,0.005031178,0.00001538078],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958279,0.002453645,0.000692945,0.000058581,0.00002878341,0.00001163381,0.00009916813,0.00003710512,0.0007903192],"genre_scores_gemma":[0.9971227,0.0007519799,0.0005113592,0.0000793338,0.00002206081,0.00002587882,0.0001754553,0.00001028627,0.001300829],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008742173,"threshold_uncertainty_score":0.002924562,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009596362732675163,"score_gpt":0.239950743617305,"score_spread":0.2303543808846298,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}