{"id":"W4409538399","doi":"10.1007/s40487-025-00334-6","title":"On the Horizon: A Global Multidisciplinary Perspective on Delivering Emerging Therapies for Patients with BCG-Naïve High-Risk NMIBC","year":2025,"lang":"en","type":"article","venue":"Oncology and Therapy","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"Daiichi Sankyo Europe; EMD Serono; EUSA Pharma; Astellas Pharma; Genentech; UroGen Pharma; Eisai; Ipsen; Mirati Therapeutics; Gilead Sciences; Merck KGaA; Advanced Accelerator Applications; Amgen; Pfizer; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Multidisciplinary approach; Perspective (graphical); Medicine; Horizon; Intensive care medicine; Computer science; Sociology; Physics; Artificial intelligence; Astronomy; Social science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008609783,0.0005439916,0.0008095788,0.000696671,0.002879684,0.006137758,0.001489781,0.005432863,0.01020685],"category_scores_gemma":[0.01392853,0.0002929173,0.001182622,0.0007261594,0.001805735,0.006470972,0.007716171,0.009541709,0.001998398],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003358975,"about_ca_system_score_gemma":0.01599416,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002548826,"about_ca_topic_score_gemma":0.008875666,"domain_scores_codex":[0.9934574,0.003398673,0.0003427788,0.0004602943,0.0008645092,0.001476364],"domain_scores_gemma":[0.9808287,0.002682513,0.00128246,0.000207679,0.002696414,0.01230226],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000430522,0.0004910802,0.006931006,0.002787861,0.0002138044,0.001228531,0.004574777,0.001622538,0.00186295,0.02045001,0.4407443,0.5186626],"study_design_scores_gemma":[0.000332225,0.001246349,0.01004572,0.01128314,0.0003373637,0.001609459,0.01429589,0.001607996,0.0007977784,0.04431558,0.9139291,0.0001993214],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.005452669,0.07055818,0.003578877,0.8985403,0.008386686,0.0000677986,0.0001185258,0.0001213649,0.0131756],"genre_scores_gemma":[0.1520327,0.1801338,0.02013285,0.6046145,0.03264518,0.0004437477,0.0005464197,0.0002681139,0.009182661],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.01020685,"threshold_uncertainty_score":0.04553342,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005897211184523203,"score_gpt":0.262218595216976,"score_spread":0.2563213840324528,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}