{"id":"W4409548049","doi":"10.1016/j.biosx.2025.100621","title":"Paper discs in a 3D printed microplate hybrid microfluidic device for low-cost, rapid, and ultrasensitive paper-based bioluminescence detection of human epidermal growth factor receptor 2 (HER2) breast cancer biomarker","year":2025,"lang":"en","type":"article","venue":"Biosensors and Bioelectronics X","topic":"Biosensors and Analytical Detection","field":"Engineering","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"McGill University","keywords":"Human Epidermal Growth Factor Receptor 2; Bioluminescence; Human breast; Biomarker; Epidermal growth factor receptor; Microfluidics; Breast cancer; Epidermal growth factor; Chemistry; Materials science; Cancer; Receptor; Nanotechnology; Medicine; Biochemistry; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005297036,0.000904636,0.0006055341,0.0007981497,0.0002684621,0.0006269813,0.001791095,0.001271266,0.001729616],"category_scores_gemma":[0.0007254529,0.0005240304,0.0007662179,0.0004433648,0.0002545509,0.0006085119,0.0004633399,0.0004286471,0.001411808],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004347598,"about_ca_system_score_gemma":0.0002741594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002784044,"about_ca_topic_score_gemma":0.0003526319,"domain_scores_codex":[0.9990319,0.0001066852,0.0001115051,0.0002909574,0.0003974493,0.0000615913],"domain_scores_gemma":[0.9995096,0.000132858,0.0001399638,0.00007210677,0.0001066831,0.00003877657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001626766,0.00009504784,0.0007340817,0.000469875,0.00004278715,0.0004955559,0.00005650372,0.0006507275,0.9701933,0.0004301941,0.001728737,0.02494034],"study_design_scores_gemma":[0.00003097709,0.0004164696,0.002533582,0.00002606274,0.00005553852,0.0009188555,0.00002667114,0.007239698,0.9734097,0.0001371824,0.01514654,0.00005872849],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.4461107,0.0147568,0.505166,0.001557936,0.003451461,0.0009763043,0.004529246,0.01141762,0.01203386],"genre_scores_gemma":[0.616254,0.004375744,0.3613634,0.001186725,0.0003565606,0.0009335573,0.002283585,0.0001781973,0.01306824],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001791095,"threshold_uncertainty_score":0.005786121,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008096210114422147,"score_gpt":0.2318220751217844,"score_spread":0.2237258650073623,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}