{"id":"W4409575037","doi":"10.1182/bloodadvances.2024015288","title":"Delayed T-cell recovery after hematopoietic cell transplantation is associated with decreased overall survival in adults","year":2025,"lang":"en","type":"article","venue":"Blood Advances","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Office of Naval Research; Legend Biotech; Pharmacyclics; Takeda Oncology; Health Resources and Services Administration; National Institutes of Health; MorphoSys; Seagen; Astellas Pharma; Adaptive Biotechnologies; Pfizer; Incyte; Kiadis Pharma; bluebird bio; Medac; Jazz Pharmaceuticals; BeiGene; HistoGenetics; Atara Biotherapeutics; CareDx; Actinium Pharmaceuticals; National Cancer Institute; Gilead Sciences; Sanofi; GlaxoSmithKline; CSL Behring; Bristol-Myers Squibb; AstraZeneca; Gateway for Cancer Research; Swedish Orphan Biovitrum; Omeros Corporation; Vertex Pharmaceuticals; Alexion Pharmaceuticals; Mallinckrodt Pharmaceuticals; Astellas Pharma US; Amgen; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation","keywords":"Medicine; Calcineurin; Internal medicine; Transplantation; Hematopoietic stem cell transplantation; Cyclophosphamide; Anti-thymocyte globulin; Hematopoietic cell; Cumulative incidence; Immunology; T cell; Gastroenterology; Young adult; Haematopoiesis; Immune system; Oncology; Stem cell; Chemotherapy; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001908226,0.0002841727,0.0004766763,0.0002269482,0.0000454111,0.00002257965,0.00009199347,0.0001583113,0.0001155648],"category_scores_gemma":[0.00002490503,0.0002506944,0.00009665513,0.0004468292,0.00004871261,0.000227517,0.000006284309,0.0002051062,0.00002237284],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006292194,"about_ca_system_score_gemma":0.0001907747,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008544506,"about_ca_topic_score_gemma":0.0005963257,"domain_scores_codex":[0.9981669,0.0001015014,0.0004954495,0.0004755156,0.0003928755,0.0003677671],"domain_scores_gemma":[0.9990606,0.0003415512,0.00013464,0.0002456019,0.0001056704,0.0001118913],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0334843,0.006706835,0.9154246,0.01337888,0.0005934711,0.003667562,0.007008496,0.0004032339,0.0169886,0.0001407957,0.0001627645,0.002040461],"study_design_scores_gemma":[0.06257156,0.00226334,0.4872145,0.01396032,0.002729662,0.0001822118,0.001132337,0.0002653693,0.4269666,0.001010862,0.0004107773,0.001292487],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9824961,0.00167768,0.001431101,0.0001706748,0.0001451942,0.0007374771,0.00008626003,0.00009022222,0.01316523],"genre_scores_gemma":[0.9954083,0.001362068,0.001251818,0.0005281635,0.00002133305,0.0001189163,0.0002239358,0.00003328122,0.001052208],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4282101,"threshold_uncertainty_score":0.9999945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005061069500360093,"score_gpt":0.2282272764030026,"score_spread":0.2231662069026425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}