{"id":"W4409575037","doi":"10.1182/bloodadvances.2024015288","title":"Delayed T-cell recovery after hematopoietic cell transplantation is associated with decreased overall survival in adults","year":2025,"lang":"en","type":"article","venue":"Blood Advances","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Office of Naval Research; Legend Biotech; Pharmacyclics; Takeda Oncology; Health Resources and Services Administration; National Institutes of Health; MorphoSys; Seagen; Astellas Pharma; Adaptive Biotechnologies; Pfizer; Incyte; Kiadis Pharma; bluebird bio; Medac; Jazz Pharmaceuticals; BeiGene; HistoGenetics; Atara Biotherapeutics; CareDx; Actinium Pharmaceuticals; National Cancer Institute; Gilead Sciences; Sanofi; GlaxoSmithKline; CSL Behring; Bristol-Myers Squibb; AstraZeneca; Gateway for Cancer Research; Swedish Orphan Biovitrum; Omeros Corporation; Vertex Pharmaceuticals; Alexion Pharmaceuticals; Mallinckrodt Pharmaceuticals; Astellas Pharma US; Amgen; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation","keywords":"Medicine; Calcineurin; Internal medicine; Transplantation; Hematopoietic stem cell transplantation; Cyclophosphamide; Anti-thymocyte globulin; Hematopoietic cell; Cumulative incidence; Immunology; T cell; Gastroenterology; Young adult; Haematopoiesis; Immune system; Oncology; Stem cell; Chemotherapy; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003056821,0.0002088534,0.0002559718,0.0002629854,0.0001665911,0.000323213,0.0001584856,0.0003248354,0.001185097],"category_scores_gemma":[0.0008931427,0.00008855319,0.0002002549,0.0002827341,0.0001624259,0.0002341961,0.0002225995,0.000415879,0.0001839147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001442641,"about_ca_system_score_gemma":0.0001825834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003597066,"about_ca_topic_score_gemma":0.0003918402,"domain_scores_codex":[0.9998621,0.00003008762,0.00001973452,0.00003015156,0.00002416511,0.00003368671],"domain_scores_gemma":[0.9993646,0.00007643751,0.0003654101,0.0000228094,0.00004474424,0.0001260759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004562052,0.00003193463,0.9951922,0.00001467248,0.00002911646,0.0001967706,0.00003158329,0.00005066527,0.0009333806,0.00001740569,0.0001161974,0.002930007],"study_design_scores_gemma":[0.00002460372,0.0006632588,0.9961743,0.00001422417,0.00005726114,0.001749051,0.00008275264,0.0003006482,0.0004615772,0.00004865579,0.0004197271,0.00000388441],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991924,0.0004141825,0.00007170501,0.00002874763,0.00000449349,0.000002865983,0.0001139771,0.000004354991,0.0001672574],"genre_scores_gemma":[0.9995837,0.00009227327,0.00004919106,0.00002233103,0.000009530195,0.000002741781,0.000180283,9.321861e-7,0.00005900057],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001185097,"threshold_uncertainty_score":0.003964543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005061069500360093,"score_gpt":0.2282272764030026,"score_spread":0.2231662069026425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}