{"id":"W4409577498","doi":"10.1016/j.isci.2025.112472","title":"Consecutive low-frequency shifts in A/T content denote nucleosome positions across microeukaryotes","year":2025,"lang":"en","type":"article","venue":"iScience","topic":"Genomics and Phylogenetic Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Education and Child Care","funders":"Biological and Environmental Research; Office of Science; U.S. Department of Energy","keywords":"Content (measure theory); Nucleosome; Chemistry; Nuclear magnetic resonance; Physics; Mathematics; Biochemistry; Histone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008529793,0.0001245599,0.0001360165,0.0002706257,0.0001508627,0.0002382699,0.0001132347,0.0001817455,0.0006451295],"category_scores_gemma":[0.0003040646,0.0001168099,0.0001791979,0.0002276473,0.0001307651,0.0001463373,0.0002016201,0.0002190248,0.000183663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001405163,"about_ca_system_score_gemma":0.0001045499,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00192368,"about_ca_topic_score_gemma":0.004140471,"domain_scores_codex":[0.9999429,0.000004191763,0.000003678048,0.00003030628,0.000009838388,0.000009056644],"domain_scores_gemma":[0.9998866,0.000037148,0.00003535079,0.000009288497,0.00001580984,0.00001572225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002644,0.00002690894,0.06703547,0.000104515,0.0000537321,0.00009561359,0.00009717674,0.007332798,0.9013612,0.0005148062,0.0001751226,0.02293834],"study_design_scores_gemma":[0.00001307926,0.0002149572,0.517916,0.00003459117,0.0001377224,0.000695658,0.0002125242,0.1022651,0.3730482,0.001458558,0.003971167,0.00003248697],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873068,0.0002617506,0.01121419,0.00002420362,0.000003802326,0.000004057867,0.0005392519,0.0001120395,0.0005338584],"genre_scores_gemma":[0.9939564,0.000109963,0.004915706,0.00002192388,0.000001618769,0.0000045016,0.0006879237,0.00001883824,0.0002830314],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00192368,"threshold_uncertainty_score":0.003824949,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01482417307440501,"score_gpt":0.2730980029455293,"score_spread":0.2582738298711242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}