{"id":"W4409625223","doi":"10.1158/1538-7445.am2025-243","title":"Abstract 243: FLT4, a novel regulator of renal cell carcinoma progression","year":2025,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Regulator; Renal cell carcinoma; Cancer research; Medicine; Clear cell renal cell carcinoma; Biology; Internal medicine; Pathology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001322172,0.000321268,0.0002064362,0.0003897311,0.0002517111,0.0004653947,0.0003086381,0.000317556,0.002518072],"category_scores_gemma":[0.0001444951,0.0000896159,0.0002343871,0.0002287031,0.0001626016,0.0002080723,0.0001637516,0.0002670646,0.0005400973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007955916,"about_ca_system_score_gemma":0.0003785857,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001272133,"about_ca_topic_score_gemma":0.0009844763,"domain_scores_codex":[0.9999074,0.000008369366,0.000005615514,0.00002760678,0.00003165336,0.00001938575],"domain_scores_gemma":[0.9999362,0.000007301911,0.00002631837,0.000004067398,0.00001250518,0.0000135206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004198741,0.00006102123,0.00751176,0.000161467,0.00003172077,0.0009183032,0.00002774673,0.0005364252,0.9765351,0.0006022413,0.001245688,0.01194879],"study_design_scores_gemma":[0.0001437733,0.000655842,0.1264033,0.0000304749,0.0001573425,0.004810152,0.00008260096,0.01015554,0.8253783,0.0008782498,0.03126456,0.00003990811],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9798509,0.007343914,0.004477924,0.0005208704,0.0001216928,0.00007604982,0.002598657,0.0004263318,0.004583599],"genre_scores_gemma":[0.9899594,0.0009474289,0.001844299,0.0001126509,0.0000580461,0.00003674861,0.00244792,0.00001881477,0.004574615],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.002518072,"threshold_uncertainty_score":0.008423746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03490003839513737,"score_gpt":0.3787704806670403,"score_spread":0.3438704422719029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}