{"id":"W4409629661","doi":"10.1158/1538-7445.am2025-3927","title":"Abstract 3927: Bone Metastasis Technology Platform: Establishing clinically relevant bone metastasis models for breast and prostate cancer and multiple myeloma","year":2025,"lang":"en","type":"article","venue":"Cancer Research","topic":"Medical Imaging and Pathology Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Micropharma (Canada)","funders":"","keywords":"Prostate cancer; Medicine; Bone metastasis; Multiple myeloma; Metastasis; Breast cancer; Oncology; Prostate; Breast cancer metastasis; Cancer; Internal medicine; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003036907,0.0002585759,0.0008615963,0.0006633849,0.0004938298,0.00008412509,0.0001589627,0.0002419289,0.00003491291],"category_scores_gemma":[0.002444684,0.000200763,0.00008780195,0.0007401254,0.001414553,0.000238527,0.0003832837,0.001161423,0.000002163173],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001435042,"about_ca_system_score_gemma":0.0005815746,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008441616,"about_ca_topic_score_gemma":0.0003730173,"domain_scores_codex":[0.9970818,0.00007562552,0.0006401084,0.0008143746,0.0004821197,0.0009060129],"domain_scores_gemma":[0.997094,0.001336249,0.000117516,0.0004150006,0.0007377813,0.0002994137],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.002899952,0.0002182063,0.0339242,0.002102104,0.0009497255,0.0002550755,0.0009664472,0.00004156035,0.01310887,0.0007129236,0.01350839,0.9313126],"study_design_scores_gemma":[0.1081288,0.00654022,0.2891497,0.0293748,0.00876606,0.003090942,0.03970778,0.0590731,0.06175323,0.1128292,0.2759824,0.005603751],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8911359,0.05146514,0.000636414,0.05351713,0.0002234052,0.001632869,0.0007671261,0.0001298075,0.0004922377],"genre_scores_gemma":[0.9681776,0.02252691,0.005481659,0.0007027617,0.0001455284,0.001030597,0.00002538135,0.00004503157,0.001864533],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9257088,"threshold_uncertainty_score":0.8186877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1194129501964481,"score_gpt":0.4426454095660564,"score_spread":0.3232324593696083,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}