{"id":"W4409630666","doi":"10.1158/1538-7445.am2025-1269","title":"Abstract 1269: Development of humanized PDX mouse model for high grade serous ovarian cancer","year":2025,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; Spinal Cord Injury BC; University of British Columbia","funders":"","keywords":"Serous ovarian cancer; Ovarian cancer; Serous fluid; Cancer; Medicine; Cancer research; Internal medicine; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004311452,0.0005838026,0.0004027368,0.0009131508,0.0002873175,0.0004532849,0.0003938694,0.0008252201,0.003588293],"category_scores_gemma":[0.0001292699,0.0002861093,0.0005404544,0.0003849941,0.000406539,0.0005606707,0.0003008093,0.001349692,0.001301735],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003828618,"about_ca_system_score_gemma":0.0003588721,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005986862,"about_ca_topic_score_gemma":0.0006978522,"domain_scores_codex":[0.9996808,0.00003487117,0.00003917427,0.00009389088,0.00009307043,0.00005819202],"domain_scores_gemma":[0.9998201,0.00001812106,0.0000512977,0.00003255178,0.00001723467,0.00006080539],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006895132,0.0006316501,0.0006585586,0.0001594838,0.00001798764,0.0003358423,0.00007616988,0.000239224,0.9901305,0.0007363836,0.0009915553,0.005333203],"study_design_scores_gemma":[0.0003861756,0.005141344,0.006702802,0.00006508944,0.00008339051,0.003376409,0.0001085747,0.002818769,0.9481141,0.0003616376,0.03281564,0.00002603862],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9503895,0.004246711,0.02364527,0.0008862693,0.0004965154,0.001095083,0.00863912,0.001015934,0.009585657],"genre_scores_gemma":[0.938959,0.003957293,0.01676578,0.0004262401,0.00008282095,0.001605774,0.007760227,0.0001560692,0.03028684],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003588293,"threshold_uncertainty_score":0.01200402,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08888913685801408,"score_gpt":0.4299541915022643,"score_spread":0.3410650546442502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}