{"id":"W4409632815","doi":"10.1158/1538-7445.am2025-6445","title":"Abstract 6445: Atypical teratoid rhabdoid tumor development mirrors developmental programs","year":2025,"lang":"en","type":"article","venue":"Cancer Research","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Atypical teratoid rhabdoid tumor; Pathology; Medicine; Biology; Medulloblastoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001153807,0.0007826873,0.0008084521,0.001308705,0.0007430508,0.00137698,0.0005826778,0.000653096,0.004877933],"category_scores_gemma":[0.00189807,0.0003767336,0.001027271,0.001331027,0.0003727174,0.0006696268,0.001093901,0.0008079416,0.005123192],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006401663,"about_ca_system_score_gemma":0.00106226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004700757,"about_ca_topic_score_gemma":0.01120722,"domain_scores_codex":[0.9989881,0.00007557185,0.00005944977,0.0005439264,0.0002478794,0.00008515648],"domain_scores_gemma":[0.9992408,0.0002611787,0.0001118712,0.0001372234,0.0001797307,0.00006927455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001047442,0.0001725692,0.1118387,0.001897214,0.0005715968,0.000763362,0.0007017905,0.02041711,0.6870924,0.004218766,0.06539706,0.105882],"study_design_scores_gemma":[0.0002001915,0.0005498109,0.3632534,0.0002876766,0.0005447703,0.002109567,0.0005619804,0.1229939,0.3118427,0.009591709,0.1878641,0.0002002388],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4860339,0.002266166,0.1392684,0.0007211475,0.0002459354,0.0002867687,0.3191001,0.04077444,0.01130327],"genre_scores_gemma":[0.3502577,0.001183897,0.1547448,0.0005340052,0.00006069144,0.0005329783,0.4823329,0.004733764,0.005619238],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004877933,"threshold_uncertainty_score":0.01631826,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06988506179752633,"score_gpt":0.3999533630841391,"score_spread":0.3300683012866128,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}