{"id":"W4409648185","doi":"10.1089/jamp.2024.0039","title":"The Influence of Pressurized Metered Dose Inhaler Actuator Orifice Diameter on Regional Extrathoracic Deposition of Inhaled Epinephrine","year":2025,"lang":"en","type":"article","venue":"Journal of Aerosol Medicine and Pulmonary Drug Delivery","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Supratek Pharma (Canada); University of Alberta","funders":"","keywords":"Metered-dose inhaler; Body orifice; Inhaler; Epinephrine; Deposition (geology); Medicine; Anesthesia; Internal medicine; Asthma; Anatomy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001020058,0.0002462573,0.0007703599,0.0004468735,0.0001434187,0.00001199025,0.0001925755,0.0001351667,0.00003335753],"category_scores_gemma":[0.0003480499,0.0001453832,0.0002140974,0.0004198439,0.0004892854,0.0002557133,0.00005159748,0.0004844877,0.000001772268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004383875,"about_ca_system_score_gemma":0.0002791516,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003347504,"about_ca_topic_score_gemma":0.000002734168,"domain_scores_codex":[0.9972644,0.0002767122,0.001339962,0.0002113895,0.0006888997,0.0002186579],"domain_scores_gemma":[0.9963495,0.001078882,0.0009688651,0.0003343355,0.001093945,0.0001745021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01506667,0.0010482,0.003688047,0.001392164,0.001055229,0.00120723,0.001357035,0.0002585084,0.9352825,0.00012841,0.01072691,0.0287891],"study_design_scores_gemma":[0.04758446,0.01361145,0.207479,0.0429303,0.008007964,0.009866447,0.008352814,0.003925422,0.6347241,0.000714822,0.0208865,0.001916634],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893354,0.006225509,0.00004986093,0.00303479,0.0002859941,0.0003638944,0.000007031153,0.000009890847,0.0006875906],"genre_scores_gemma":[0.9935229,0.003611311,0.0003597986,0.001635766,0.0002696984,0.000007082007,0.000007497853,0.00001624709,0.0005697291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3005584,"threshold_uncertainty_score":0.5928556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0191015423083598,"score_gpt":0.2866602461044388,"score_spread":0.267558703796079,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}