{"id":"W4409655024","doi":"10.1021/acs.est.4c13689","title":"Xenometabolomics in Ecotoxicology: Concepts and Applications","year":2025,"lang":"en","type":"review","venue":"Environmental Science & Technology","topic":"Metabolomics and Mass Spectrometry Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Global Institute for Water Security; University of Saskatchewan","funders":"Fisheries and Oceans Canada; Natural Sciences and Engineering Research Council of Canada; Global Water Futures; University of Saskatchewan","keywords":"Ecotoxicology; Environmental science; Environmental chemistry; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001307095,0.001323278,0.00176704,0.003847822,0.0003462109,0.001717784,0.001326905,0.001908329,0.003764541],"category_scores_gemma":[0.001015961,0.0004404759,0.0007516305,0.004201929,0.001491194,0.0028693,0.001271399,0.003170774,0.002259891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001261055,"about_ca_system_score_gemma":0.001469782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001297629,"about_ca_topic_score_gemma":0.001562405,"domain_scores_codex":[0.9995732,0.00008792745,0.00004483765,0.00008264235,0.0001759716,0.00003548615],"domain_scores_gemma":[0.9992241,0.0004136217,0.00008533442,0.0000361937,0.0001847262,0.0000560471],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006475065,0.0001146165,0.0002771171,0.01939377,0.0001346388,0.0003381028,0.0001040009,0.001025244,0.005263124,0.02689181,0.02260762,0.9237852],"study_design_scores_gemma":[0.00000695705,0.00008833205,0.0006002448,0.002499163,0.00005567602,0.0009279235,0.00007249841,0.0001811086,0.001096737,0.009634791,0.9848067,0.0000297785],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000806387,0.9980761,0.0004642164,0.0002635128,0.0001962096,0.000003751105,0.0000128298,0.000008135045,0.00089459],"genre_scores_gemma":[0.0007074398,0.9977782,0.0004420989,0.000243259,0.0002349946,0.000007477314,0.00002316754,0.000002604115,0.0005607283],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003847822,"threshold_uncertainty_score":0.01259363,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007397715404358842,"score_gpt":0.2953909089071012,"score_spread":0.2879931935027424,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}