{"id":"W4409668804","doi":"10.17504/protocols.io.dm6gpzrkdlzp/v2","title":"Enterovirus D68 3C protease small scale expression and purification protocol v2","year":2024,"lang":"en","type":"preprint","venue":"","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Discovery Centre","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Virology; Scale (ratio); Protease; Biology; Protocol (science); Computational biology; Computer science; Geography; Medicine; Enzyme; Cartography; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008940698,0.001724553,0.001440733,0.001301534,0.001161809,0.001454223,0.001587199,0.0008001522,0.0203887],"category_scores_gemma":[0.001208473,0.001157408,0.0009832301,0.001254244,0.0005228599,0.0005909188,0.001061084,0.003713909,0.03431777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007401526,"about_ca_system_score_gemma":0.001027701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00214639,"about_ca_topic_score_gemma":0.002292301,"domain_scores_codex":[0.9988874,0.0001456875,0.0001079399,0.000220445,0.0003994234,0.0002392306],"domain_scores_gemma":[0.9995438,0.00008797032,0.0000314193,0.0001487866,0.0001053022,0.00008261549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005718598,0.0001544723,0.000308893,0.0008818872,0.00004746803,0.0002166359,0.0001852782,0.0003173183,0.9379485,0.002932053,0.03829835,0.01813726],"study_design_scores_gemma":[0.0001353401,0.0001700383,0.001342832,0.0001108894,0.0000594492,0.0006806566,0.00005593722,0.001352556,0.7003333,0.001257101,0.2944291,0.00007288309],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"protocol","genre_scores_codex":[0.1152637,0.009953957,0.595011,0.00251857,0.003867256,0.01146694,0.1793967,0.02004239,0.06247947],"genre_scores_gemma":[0.123254,0.008722391,0.3143926,0.001067123,0.0004302249,0.01007793,0.4140873,0.00669702,0.1212715],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.0203887,"threshold_uncertainty_score":0.06820697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0511697866367974,"score_gpt":0.3660540437130197,"score_spread":0.3148842570762224,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}