{"id":"W4409687753","doi":"10.3390/bioengineering12050434","title":"An Injectable Kartogenin-Incorporated Hydrogel Supports Mesenchymal Stem Cells for Cartilage Tissue Engineering","year":2025,"lang":"en","type":"article","venue":"Bioengineering","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Natural Science Foundation of China","keywords":"Mesenchymal stem cell; Chondrogenesis; Self-healing hydrogels; Cartilage; In vivo; Biomedical engineering; Biocompatibility; Regeneration (biology); Tissue engineering; Materials science; Scaffold; Osteoarthritis; Chemistry; Cell biology; Anatomy; Pathology; Medicine; Biotechnology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000944202,0.0002989236,0.0001108338,0.0002063955,0.00007020826,0.0001395263,0.0001045094,0.0002127938,0.0007417939],"category_scores_gemma":[0.00007890098,0.00007534881,0.0001638897,0.000107289,0.0001343417,0.0002074776,0.0001264716,0.0001415513,0.0001482023],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002080707,"about_ca_system_score_gemma":0.0001668246,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002307222,"about_ca_topic_score_gemma":0.0006055047,"domain_scores_codex":[0.9999565,0.000004593075,0.00000424268,0.0000116699,0.00001529562,0.00000770818],"domain_scores_gemma":[0.9999362,0.00001132615,0.00003039667,0.000002818151,0.000006963108,0.00001229899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001535359,0.00000738567,0.000068009,0.00002867085,0.000001699965,0.00001640625,0.000003607357,0.00008584175,0.9988931,0.00002296028,0.000008288567,0.0008487658],"study_design_scores_gemma":[0.00001101371,0.0002033738,0.001345917,0.000006278211,0.0000129587,0.0001284099,0.000006647461,0.0009669063,0.996064,0.00001610439,0.001233191,0.000005115963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990778,0.001495185,0.006087225,0.00005439192,0.0000301997,0.00004254833,0.0001863523,0.00006095186,0.001265137],"genre_scores_gemma":[0.9923922,0.0006618278,0.00580736,0.00003249392,0.000008215846,0.00003142327,0.0001302712,0.00001031473,0.0009259298],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007417939,"threshold_uncertainty_score":0.00248152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009313999539652219,"score_gpt":0.2397726323781948,"score_spread":0.2304586328385426,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}