{"id":"W4409689373","doi":"10.1158/1538-7445.am2025-2777","title":"Abstract 2777: Smoking, clonal evolution, and lung cancer risk","year":2025,"lang":"en","type":"article","venue":"Cancer Research","topic":"Nutrition, Genetics, and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Lung cancer; Medicine; Cancer; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005244823,0.0002100833,0.0003121018,0.0008008085,0.0002792357,0.0008508664,0.0003963889,0.0003093035,0.008428644],"category_scores_gemma":[0.001427022,0.0001457871,0.000376442,0.0008291901,0.0001468001,0.0002839091,0.0003554183,0.0003542875,0.001517738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002069384,"about_ca_system_score_gemma":0.0003233178,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001875594,"about_ca_topic_score_gemma":0.00274303,"domain_scores_codex":[0.9997306,0.00003537346,0.0000149612,0.0001152811,0.00008099894,0.00002264088],"domain_scores_gemma":[0.999467,0.0002312281,0.0001092571,0.00005182224,0.00007271448,0.00006801888],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001005736,0.0001480508,0.7959862,0.000610934,0.0005210096,0.0003247688,0.0002677023,0.003056069,0.0713052,0.001303022,0.01888413,0.1065872],"study_design_scores_gemma":[0.00007032777,0.0002496308,0.9317468,0.00008598006,0.0003730372,0.0009880883,0.00011618,0.0159778,0.02077257,0.002708917,0.02686935,0.00004136541],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9352276,0.002811918,0.01451037,0.0008892709,0.00009335147,0.00006134295,0.03886075,0.002205619,0.00533982],"genre_scores_gemma":[0.9380178,0.001393845,0.01470503,0.0004152019,0.0001033026,0.00007480341,0.04083516,0.0004511541,0.004003571],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008428644,"threshold_uncertainty_score":0.02819657,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01975765811974841,"score_gpt":0.3855937899595087,"score_spread":0.3658361318397603,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}