{"id":"W4409691549","doi":"10.1158/1538-7445.am2025-584","title":"Abstract 584: Preclinical efficacy and safety of [161Tb]Tb-labeled anti-nectin-4 radioimmunoconjugate as theranostic against triple-negative breast cancer (TNBC) and non-small cell lung cancer (NSCLC)","year":2025,"lang":"en","type":"article","venue":"Cancer Research","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Université Laval","funders":"","keywords":"Triple-negative breast cancer; Medicine; Cancer; Breast cancer; Oncology; Cancer research; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002951166,0.0004396845,0.0005058031,0.0002820295,0.0001820813,0.0002558434,0.0003790643,0.0005373171,0.003494256],"category_scores_gemma":[0.0001658699,0.0002000789,0.0002905171,0.0001513665,0.0002513737,0.0003078229,0.000127145,0.0007865023,0.001102353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004134337,"about_ca_system_score_gemma":0.0004831681,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009726853,"about_ca_topic_score_gemma":0.0006224642,"domain_scores_codex":[0.9998565,0.00002842533,0.00001177825,0.00003171668,0.000033746,0.00003786906],"domain_scores_gemma":[0.9998907,0.00001469335,0.0000307777,0.00001347303,0.00002138496,0.00002909581],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004119764,0.001535909,0.0003309884,0.0001951114,0.00003197523,0.0001155215,0.00004452494,0.0004308591,0.9827589,0.0001648144,0.0007151734,0.009556457],"study_design_scores_gemma":[0.000604426,0.02565395,0.001983509,0.00001943314,0.0001074729,0.0003540757,0.00002643331,0.001433864,0.9649459,0.00005191669,0.004808418,0.00001081209],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923518,0.001844027,0.001809535,0.0001758052,0.0000877374,0.0001810825,0.0004985845,0.0001707702,0.002880713],"genre_scores_gemma":[0.9842936,0.001715428,0.002038378,0.0001285075,0.00004156781,0.0002716561,0.001830942,0.00006706399,0.009612851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003494256,"threshold_uncertainty_score":0.01168948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05146596342221781,"score_gpt":0.4413332187591838,"score_spread":0.389867255336966,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}