{"id":"W4409699503","doi":"10.22215/cujs.v3i2.4825","title":"Caspase Activation in an In-Vitro Model of Parkinson’s Disease","year":2025,"lang":"en","type":"article","venue":"Carleton undergraduate journal of science.","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"","keywords":"Parkinson's disease; In vitro; Neuroscience; Apoptosis; Caspase 3; Caspase; Disease; Medicine; Chemistry; Biology; Internal medicine; Biochemistry; Programmed cell death","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002146105,0.0001263484,0.0002689569,0.001686082,0.00007605531,0.000136044,0.001291483,0.00003106368,6.59646e-7],"category_scores_gemma":[0.0004379541,0.0001170464,0.00008483868,0.002703114,0.0003361813,0.002738599,0.0002005527,0.0002356967,3.287774e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004507381,"about_ca_system_score_gemma":0.002625668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002885593,"about_ca_topic_score_gemma":0.0000120147,"domain_scores_codex":[0.9977659,0.0001874834,0.0006569307,0.0003169058,0.0008002491,0.0002725067],"domain_scores_gemma":[0.9984363,0.0002278027,0.0003768089,0.0003423889,0.0004287405,0.0001879451],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0001510912,0.0002633837,0.002870419,0.00002754756,0.000005239896,0.00002568126,0.0006082961,0.813952,0.124345,0.04184861,0.00004598758,0.01585664],"study_design_scores_gemma":[0.0005725096,0.00004456659,0.02166562,0.0001151307,0.000004935556,0.000003418,0.0000945304,0.7929493,0.03110373,0.1533285,0.00001595115,0.0001017681],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.652034,0.00004343101,0.3444958,0.002863836,0.0002509755,0.00007749041,0.000001169733,0.000005762432,0.0002275305],"genre_scores_gemma":[0.9611202,0.00001860034,0.03857041,0.0002430243,0.00001779133,0.00000229361,5.142832e-7,0.000003926946,0.00002318367],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3090863,"threshold_uncertainty_score":0.4773015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02845761080004406,"score_gpt":0.3189584101514484,"score_spread":0.2905007993514043,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}