{"id":"W4409702401","doi":"10.1177/10406387251331933","title":"Identification of fibrinogen Aα-chain as an amyloid precursor protein in a case of canine coronary artery amyloidosis","year":2025,"lang":"en","type":"article","venue":"Journal of Veterinary Diagnostic Investigation","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Japan Society for the Promotion of Science","keywords":"Amyloidosis; Fibrinogen; Amyloid (mycology); Serum Amyloid A Protein; Serum amyloid A; Pathology; Pathogenesis; Coronary arteries; Medicine; Chemistry; Internal medicine; Artery; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003613726,0.0003771127,0.0005210211,0.001255503,0.0007448341,0.0004662917,0.0002436086,0.001243465,0.0005338096],"category_scores_gemma":[0.0009385041,0.0003459012,0.000370943,0.0005148518,0.0009187699,0.0003493165,0.0004950287,0.0006100249,0.000157196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004780331,"about_ca_system_score_gemma":0.000237849,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001786669,"about_ca_topic_score_gemma":0.002415068,"domain_scores_codex":[0.9997172,0.00002769424,0.00002769138,0.000089082,0.00007130625,0.00006706561],"domain_scores_gemma":[0.9994344,0.0001051194,0.0001203201,0.00003531577,0.00007670371,0.0002280911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0007555938,0.0004796802,0.2281231,0.0001567701,0.0001017588,0.6630054,0.001568141,0.0003136603,0.09938243,0.000312069,0.0004481553,0.005353223],"study_design_scores_gemma":[0.00007472668,0.001827981,0.3026279,0.00002946594,0.0001724663,0.6801439,0.0006116731,0.00246,0.01044051,0.0002744737,0.001287379,0.00004951687],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989134,0.0002609605,0.0002937986,0.000079148,0.00001171743,0.00001332912,0.00002183514,0.00001032062,0.0003954678],"genre_scores_gemma":[0.9994376,0.0001232062,0.0002451771,0.00004565362,0.00001856551,0.000002498349,0.00003958553,0.000002189663,0.00008546798],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001786669,"threshold_uncertainty_score":0.003552496,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0153860711516602,"score_gpt":0.28865464678865,"score_spread":0.2732685756369899,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}