{"id":"W4409706031","doi":"10.3390/vaccines13050439","title":"WHO Workshop Report: Regulatory Science to Inform Clinical Pathways for Shigella Vaccines Intended for Use in Children in Low- and Middle-Income Countries","year":2025,"lang":"en","type":"article","venue":"Vaccines","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"World Health Organization; Bill and Melinda Gates Foundation","keywords":"Product (mathematics); New product development; Medicine; Clinical study design; Population; Clinical trial; Business; Public relations; Environmental health; Political science; Marketing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.2203883,0.002026714,0.001345716,0.002770661,0.002803979,0.01265064,0.006895507,0.01762762,0.01298879],"category_scores_gemma":[0.1508884,0.001467958,0.004201875,0.002109295,0.004005319,0.008782935,0.00955073,0.0211166,0.006096294],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00777236,"about_ca_system_score_gemma":0.113768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01393941,"about_ca_topic_score_gemma":0.01134175,"domain_scores_codex":[0.9116121,0.05489527,0.007608741,0.003118637,0.01687529,0.005889936],"domain_scores_gemma":[0.787115,0.08968186,0.01430364,0.01016576,0.08227682,0.01645692],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003365578,0.0003828142,0.002444626,0.003051442,0.0001240254,0.0005741179,0.002055631,0.001222384,0.001900377,0.02382342,0.8397118,0.1243729],"study_design_scores_gemma":[0.0002161173,0.0002729603,0.001532839,0.005896742,0.0001294067,0.0001624296,0.001303556,0.000490946,0.002133977,0.01498172,0.9727795,0.00009981405],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.001963332,0.01464658,0.01532658,0.9011041,0.0228323,0.006322563,0.003928533,0.000394016,0.03348202],"genre_scores_gemma":[0.05479569,0.04783184,0.1634028,0.6233482,0.02598686,0.01910956,0.00946901,0.0009379596,0.05511807],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.2203883,"threshold_uncertainty_score":0.9614,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05397977074996593,"score_gpt":0.3772579404092434,"score_spread":0.3232781696592775,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}