{"id":"W4409713608","doi":"10.1016/j.joca.2025.02.643","title":"EP-104IAR (EXTENDED-RELEASE INTRA-ARTICULAR INJECTION OF FLUTICASONE PROPIONATE) SHOWS SUSTAINED PAIN RESPONSE FOR SUBJECTS WITH MODERATE BASELINE PAIN AND BMI LESS THAN 30 IN SPRINGBOARD, A PHASE 2, RANDOMIZED, 24-WEEK STUDY OF OSTEOARTHRITIS OF THE KNEE","year":2025,"lang":"en","type":"article","venue":"Osteoarthritis and Cartilage","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Aurinia (Canada)","funders":"","keywords":"Fluticasone propionate; Medicine; Intra articular; Randomized controlled trial; Anesthesia; Baseline (sea); Physical therapy; Internal medicine; Osteoarthritis; Alternative medicine; Biology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001603804,0.001740267,0.002338315,0.0007522022,0.0003846177,0.0006668329,0.001173678,0.001684736,0.006373688],"category_scores_gemma":[0.001114346,0.0006660713,0.00161708,0.0004263422,0.001104842,0.001065541,0.0003579608,0.003044451,0.0009400366],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003834795,"about_ca_system_score_gemma":0.0007322584,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001264435,"about_ca_topic_score_gemma":0.003647711,"domain_scores_codex":[0.9995825,0.000184422,0.00002196476,0.00005563428,0.00003973308,0.0001158395],"domain_scores_gemma":[0.9994059,0.0001738616,0.0001168723,0.00004721632,0.00003149638,0.0002247199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8977209,0.02985109,0.001003633,0.0008007988,0.0008036027,0.000148288,0.00008998902,0.0003882551,0.0228021,0.0001121182,0.001200216,0.04507904],"study_design_scores_gemma":[0.7158858,0.2723987,0.008111138,0.00003363172,0.0002890987,0.0001025243,0.00005970511,0.0004725987,0.002115859,0.00005485599,0.0004481336,0.00002811175],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993537,0.002268366,0.0006109598,0.0003243663,0.0002241655,0.0009966723,0.0006788271,0.0002311488,0.001128351],"genre_scores_gemma":[0.9903539,0.001710437,0.001694751,0.0006456471,0.0003383244,0.0008507226,0.001152252,0.00003450796,0.003219415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006373688,"threshold_uncertainty_score":0.02132207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008455840935395613,"score_gpt":0.2384978856144858,"score_spread":0.2300420446790902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}