{"id":"W4409721738","doi":"10.1101/2025.04.22.25326172","title":"Ultra-Processed Food Consumption and Colorectal Cancer Risk: A Systematic Review and Two-Stage Mediation Meta-analysis","year":2025,"lang":"en","type":"review","venue":"medRxiv","topic":"Consumer Attitudes and Food Labeling","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Meta-analysis; Colorectal cancer; Stage (stratigraphy); Medicine; Systematic review; Oncology; Risk analysis (engineering); MEDLINE; Internal medicine; Cancer; Political science; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03377498,0.004106092,0.02051803,0.005874627,0.0006690874,0.003890528,0.003878484,0.002515678,0.004496877],"category_scores_gemma":[0.05773862,0.002372752,0.05914559,0.005898258,0.0008754102,0.002797484,0.002344913,0.002467381,0.0004409332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002796472,"about_ca_system_score_gemma":0.004517452,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005210913,"about_ca_topic_score_gemma":0.009714654,"domain_scores_codex":[0.9742056,0.01764201,0.004056904,0.001878086,0.001733981,0.0004833515],"domain_scores_gemma":[0.9615302,0.02993666,0.004761022,0.001489851,0.001998009,0.0002842512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001691466,0.00003724212,0.003592945,0.1784922,0.8064508,0.0001030642,0.0000698084,0.0006317424,0.0001627629,0.0001933411,0.0003849831,0.008189676],"study_design_scores_gemma":[0.0006866415,0.000183938,0.001825633,0.009992624,0.9857266,0.00005834902,0.00002408137,0.0004544432,0.00009294149,0.0002960304,0.0006380676,0.00002078884],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01023815,0.9808457,0.004817487,0.0005079127,0.0003468589,0.001794039,0.0009280815,0.00009596532,0.0004258041],"genre_scores_gemma":[0.3779491,0.5862017,0.02047928,0.001992574,0.0005980955,0.009725581,0.001975876,0.0001006238,0.0009771135],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.03377498,"threshold_uncertainty_score":0.1786214,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07788614819397294,"score_gpt":0.3760277214492919,"score_spread":0.298141573255319,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}