{"id":"W4409728439","doi":"10.1101/2025.04.15.649022","title":"Somites are a source of nephron progenitors in zebrafish","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital","funders":"","keywords":"Zebrafish; Nephron; Progenitor cell; Progenitor; Cell biology; Biology; Kidney; Stem cell; Endocrinology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000119202,0.0002104877,0.0001675682,0.0004128241,0.0002811709,0.000307512,0.0001979208,0.0002157043,0.002141834],"category_scores_gemma":[0.0001119224,0.0002882187,0.0001769387,0.0001094645,0.000269694,0.0002006716,0.0005028124,0.0006019874,0.0007567281],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004365801,"about_ca_system_score_gemma":0.0003878096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002915695,"about_ca_topic_score_gemma":0.006752952,"domain_scores_codex":[0.9999294,0.000003860385,0.000004367016,0.00001555566,0.00003653878,0.00001012347],"domain_scores_gemma":[0.9999062,0.00001628287,0.0000252662,0.000009130188,0.00001459434,0.00002858006],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007727007,0.000003407716,0.0008847073,0.00005231737,0.000004808157,0.0001675946,0.00004803755,0.0002082003,0.9927989,0.002168058,0.000215488,0.003371076],"study_design_scores_gemma":[0.000029102,0.00009872174,0.02882361,0.00005126034,0.00003279382,0.0007228581,0.000107205,0.002202692,0.9317437,0.001062261,0.03510304,0.00002281364],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9309504,0.00367177,0.0319497,0.00061083,0.0001032126,0.00006081355,0.002829909,0.0007524297,0.02907088],"genre_scores_gemma":[0.9312789,0.002118733,0.02148789,0.0001752434,0.00002369421,0.00006880926,0.001481916,0.0003642569,0.0430006],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002915695,"threshold_uncertainty_score":0.007165134,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005709679163098002,"score_gpt":0.2048052243502331,"score_spread":0.1990955451871351,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}