{"id":"W4409782209","doi":"10.1016/j.healun.2025.02.140","title":"Anti-Donor T Cell Dynamics and Clad Risk in the Assessment of Lung Allograft Rejection - Measurement of T Cell Immune Synapses (ALARM-T) Study","year":2025,"lang":"en","type":"article","venue":"The Journal of Heart and Lung Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Immune system; ALARM; T cell; Immunological synapse; Lung; Cell; Medicine; Immunology; Biology; Internal medicine; Materials science; T-cell receptor; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001470896,0.0003430097,0.0003667453,0.0002907047,0.0002791295,0.0007840093,0.0003187599,0.0005673303,0.0006479711],"category_scores_gemma":[0.002082604,0.0001389544,0.0003323079,0.0001913105,0.0002731278,0.0003926578,0.0005095464,0.0008053105,0.0001532748],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002340445,"about_ca_system_score_gemma":0.0002183724,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004553621,"about_ca_topic_score_gemma":0.0004893659,"domain_scores_codex":[0.9994321,0.0002746207,0.00004024023,0.00009740667,0.00009279447,0.00006270219],"domain_scores_gemma":[0.9980983,0.0004625758,0.0006624223,0.0002198233,0.0001384775,0.00041838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005365774,0.0004103668,0.9837708,0.00001931934,0.0001338151,0.0001144696,0.00007671498,0.0003059859,0.003902377,0.0001064464,0.00006386298,0.005729977],"study_design_scores_gemma":[0.0001018007,0.004280462,0.9868861,0.00001150252,0.0002091793,0.0007111626,0.000211222,0.004527886,0.002549895,0.0001785863,0.0003171925,0.00001496106],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995502,0.00008324588,0.0001278712,0.000009420367,0.000004352788,0.000005365194,0.00002473394,0.000002121042,0.0001925895],"genre_scores_gemma":[0.9997597,0.00002119774,0.00007894055,0.000006942374,0.000005241428,0.000002998442,0.00002342013,8.106281e-7,0.0001007169],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001470896,"threshold_uncertainty_score":0.007778943,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01082125171700393,"score_gpt":0.2981129925959369,"score_spread":0.2872917408789329,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}