{"id":"W4409791043","doi":"10.1101/2025.04.24.25326338","title":"C-reactive protein for pulmonary tuberculosis screening and treatment response monitoring in children","year":2025,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Global Health Research","funders":"National Institute of Allergy and Infectious Diseases; University of Washington; National Institute on Aging; National Institutes of Health; Center for AIDS Research, University of Washington; Fred Hutchinson Cancer Research Center","keywords":"Pulmonary tuberculosis; Medicine; Tuberculosis; Intensive care medicine; Internal medicine; Pediatrics; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005953628,0.000484583,0.0006842796,0.0007977749,0.0002501965,0.0008527337,0.0003537521,0.0005956293,0.001821132],"category_scores_gemma":[0.01001115,0.0002553989,0.0003716268,0.0009961425,0.0003869108,0.0004280083,0.0003628084,0.0007767303,0.0004552289],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005572631,"about_ca_system_score_gemma":0.001372525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001835324,"about_ca_topic_score_gemma":0.002075348,"domain_scores_codex":[0.996981,0.002250554,0.0001261668,0.0001721728,0.0003231364,0.0001469092],"domain_scores_gemma":[0.9949402,0.002771869,0.001512495,0.0002100451,0.000300398,0.0002650437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003441822,0.0004074858,0.8869205,0.0005515846,0.0002074927,0.0003371872,0.0004212439,0.0004181063,0.003680092,0.0003669029,0.002960474,0.100287],"study_design_scores_gemma":[0.0002258359,0.003395885,0.9781966,0.0003150044,0.0002691473,0.001266314,0.0003594118,0.0025691,0.006207379,0.0004088794,0.006759713,0.00002682992],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9421304,0.03980183,0.005552839,0.004170378,0.0002076122,0.000311612,0.002020302,0.0001533281,0.005651544],"genre_scores_gemma":[0.9849859,0.004002727,0.009129293,0.0002256647,0.000139897,0.0001733837,0.0005494516,0.00002078989,0.0007729115],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005953628,"threshold_uncertainty_score":0.03148615,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04603825999826075,"score_gpt":0.3572808238166889,"score_spread":0.3112425638184281,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}