{"id":"W4409799467","doi":"10.1016/j.jinf.2025.106495","title":"Development and validation of a cephalosporin allergy clinical decision rule","year":2025,"lang":"en","type":"article","venue":"Journal of Infection","topic":"Drug-Induced Adverse Reactions","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Austin Health","keywords":"Cephalosporin; Medicine; Allergy; Intensive care medicine; Cephalosporin Antibiotic; Antibiotics; Immunology; Microbiology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006307905,0.00005643394,0.0002159961,0.0002951182,0.00003552256,0.000006318916,0.00001621272,0.00007978981,0.000007108807],"category_scores_gemma":[0.0004280829,0.00004624725,0.00008815464,0.000184992,0.00001998069,0.0001313032,0.0000161252,0.000191986,0.000003701138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001153598,"about_ca_system_score_gemma":0.0002463184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001286386,"about_ca_topic_score_gemma":0.000007779143,"domain_scores_codex":[0.9990258,0.00003026321,0.0006436524,0.00007055813,0.0001721825,0.00005751596],"domain_scores_gemma":[0.9991239,0.0001193287,0.0003419561,0.00007041265,0.0002834627,0.00006098878],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.000162108,0.0006463568,0.1222836,0.00006322117,0.0003593277,0.00001690031,0.0001592484,0.00008128207,0.01396643,0.0003383329,0.0002692912,0.8616539],"study_design_scores_gemma":[0.001539033,0.00008188494,0.9081742,0.0004134324,0.0000878645,0.0001868898,0.00006010689,0.0000295256,0.02818785,0.0002709848,0.06092916,0.00003912513],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889936,0.00004380436,0.006123411,0.0001395867,0.0007546286,0.00006894986,1.744537e-7,0.000007683802,0.003868196],"genre_scores_gemma":[0.991382,0.0003235308,0.007977128,0.0000373248,0.0001163779,9.130646e-7,0.000001476551,0.000004424771,0.0001567994],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8616148,"threshold_uncertainty_score":0.1885908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03269178186456177,"score_gpt":0.3708118269291981,"score_spread":0.3381200450646363,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}