{"id":"W4409818223","doi":"10.1111/apt.70153","title":"Letter: Re‐Examining Seton Efficacy in Perianal Crohn's Disease—Critical Considerations for Outcome Measurement and Clinical Interpretation. Authors' Reply","year":2025,"lang":"en","type":"letter","venue":"Alimentary Pharmacology & Therapeutics","topic":"Anorectal Disease Treatments and Outcomes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; McGill University Health Centre; Ottawa Hospital; University of British Columbia Hospital; University of Ottawa","funders":"","keywords":"Medicine; Interpretation (philosophy); Outcome (game theory); Crohn's disease; Dermatology; Disease; Medical physics; Surgery; Intensive care medicine; Internal medicine; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01285068,0.0008948709,0.002295066,0.001287139,0.001694135,0.00328765,0.003412789,0.02422523,0.005195822],"category_scores_gemma":[0.1278406,0.0007055791,0.0015162,0.001168728,0.003228126,0.004346594,0.001758667,0.02736562,0.005774946],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003114376,"about_ca_system_score_gemma":0.003600919,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002970442,"about_ca_topic_score_gemma":0.002524272,"domain_scores_codex":[0.9912161,0.003674298,0.001954894,0.0009329082,0.001752626,0.0004692847],"domain_scores_gemma":[0.9273577,0.04758462,0.003459142,0.002067474,0.01701662,0.002514486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001178235,0.00002278382,0.0009313115,0.0001703139,0.00003449278,0.0004510409,0.0001081901,0.00006613232,0.00007193674,0.0007152249,0.9872785,0.01003233],"study_design_scores_gemma":[0.0004362479,0.0002831374,0.004261153,0.002201108,0.0001902002,0.00648617,0.001047852,0.001639609,0.0009699689,0.01444465,0.9676753,0.0003646097],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0005538741,0.001594955,0.0002926829,0.9334632,0.06345774,0.00002363461,0.0002034161,0.00008254997,0.0003278528],"genre_scores_gemma":[0.004994234,0.001437836,0.0006306157,0.9060215,0.08540157,0.0001091409,0.00006797457,0.00004212908,0.001295091],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02422523,"threshold_uncertainty_score":0.06796175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1633479898128966,"score_gpt":0.4408030625745925,"score_spread":0.2774550727616958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}