{"id":"W4409821093","doi":"10.1158/1538-7445.am2025-lb416","title":"Abstract LB416: SAVANNAH: Clearance of plasma EGFRm in patients with EGFRm MET-overexpressed (OverExp) and/or -amplified (Amp) NSCLC post-osimertinib (osi) treated with savolitinib (savo) + osi","year":2025,"lang":"en","type":"article","venue":"Cancer Research","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"","keywords":"Osimertinib; Medicine; Internal medicine; Cancer; Adenocarcinoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007175144,0.0002444439,0.0006462689,0.0002908743,0.0002175289,0.0006098702,0.0002807959,0.0004867704,0.003390457],"category_scores_gemma":[0.0007946172,0.0001965258,0.0004665956,0.0002582163,0.0002040611,0.0004796393,0.0002464219,0.0007081847,0.0006066201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004945078,"about_ca_system_score_gemma":0.0005140207,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004535457,"about_ca_topic_score_gemma":0.00112126,"domain_scores_codex":[0.9997321,0.000102508,0.00001604761,0.00005411614,0.00004987162,0.00004534813],"domain_scores_gemma":[0.9995767,0.00008799126,0.0001156767,0.00002205739,0.00003890193,0.0001586886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.2075707,0.004549741,0.6037859,0.0004187864,0.0008806649,0.0009229504,0.0002475625,0.0009667291,0.05138046,0.0002162706,0.007967398,0.1210929],"study_design_scores_gemma":[0.01015512,0.07547525,0.8956947,0.00005877257,0.0004638573,0.001300983,0.0001760612,0.003449843,0.006509621,0.0002554596,0.006412507,0.00004785098],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9976717,0.0005965157,0.0001059756,0.0001519774,0.00001739556,0.00005912191,0.0004343083,0.00002961238,0.0009333924],"genre_scores_gemma":[0.997728,0.0001052318,0.0001979641,0.00009721037,0.00003095043,0.00005955745,0.0007583754,0.000006215784,0.001016391],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.003390457,"threshold_uncertainty_score":0.01134223,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0415253501626779,"score_gpt":0.3913617955527816,"score_spread":0.3498364453901037,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}