{"id":"W4409821534","doi":"10.1158/1538-7445.am2025-lb037","title":"Abstract LB037: CD28 drives CAR T cell responses in multiple myeloma","year":2025,"lang":"en","type":"article","venue":"Cancer Research","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Multiple myeloma; Medicine; Cancer research; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002293455,0.0003046894,0.0003043706,0.0002581255,0.0001776011,0.0003729441,0.0002398691,0.0004368876,0.002290545],"category_scores_gemma":[0.000108,0.0001736259,0.0002878832,0.0001657885,0.0002012661,0.000161934,0.000255851,0.001416842,0.0008894785],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004645142,"about_ca_system_score_gemma":0.0002843916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008029871,"about_ca_topic_score_gemma":0.0007708563,"domain_scores_codex":[0.9996746,0.00004940872,0.00002277947,0.0000628484,0.0000978538,0.00009260584],"domain_scores_gemma":[0.9999248,0.00001133793,0.00001422537,0.000009970701,0.00001164634,0.00002808084],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001379806,0.00009346444,0.00009757528,0.00002076996,0.000002782995,0.00002732116,0.00001031949,0.000126523,0.9981591,0.00007408186,0.0001143987,0.001135675],"study_design_scores_gemma":[0.00005919364,0.0009826995,0.001748051,0.000005383798,0.00001287524,0.0002047121,0.00002970805,0.00304122,0.9918508,0.00006838996,0.001992651,0.000004287817],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9933285,0.000908623,0.003099477,0.0001593039,0.00004575657,0.00005128736,0.0004454018,0.0001637923,0.001797993],"genre_scores_gemma":[0.9958944,0.0002744468,0.001120696,0.00006022584,0.0000120915,0.00004558623,0.0003828383,0.00002240395,0.002187168],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.002290545,"threshold_uncertainty_score":0.007662654,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1005221090134501,"score_gpt":0.4490982665798321,"score_spread":0.348576157566382,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}